A process for making an oligonucleotide, the process including reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position and inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel.

A process for making an oligonucleotide, the process including reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position and inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel.

A powder mixing system and method improves productivity of a final product by reducing time required for completion of mixing. The powder mixing system includes a mixing vessel provided with a rotating shaft for mixing multiple kinds of powder, a rotating machine for rotating the mixing vessel by means of the rotating shaft, an image photographing device for acquiring an image of the powder in a mixing process, and a computer. The mixing vessel includes a window through which the image of the powder is photographed. The computer has a function of detecting that the mixing vessel is located at a predetermined position. The image photographing device acquires the image of the powder through the window of the mixing vessel located at the predetermined position. The computer estimates a mixing state of the powder based on the acquired image of the powder.

A granular coating conveyor system for coating granular particles carried in compartments along a tubular conveyor member. Coating fluid is fed over the granular particles through radial nozzles located inside a co-axial rotating blender with tubular member upstream discharge port and tubular member downstream return ingress port for the granular particles. The blender is a drum having a helicoidal spiral screw integrally mounted to an interior peripheral wall face of the drum and extending therealong radially outwardly of the tubular member mixing in the drum in tumbling fashion the granular particles with coating fluid and guiding same therealong, so as to dynamically form a kidney shape mass of granular particles.

A slide gate assembly includes a mounting plate with a through opening and an upper surface, and a top plate with a through opening and lower surface, wherein the through opening of the top plate aligns with the through opening of the mounting plate. A slide plate is mounted between the lower surface of the top plate and the upper surface of the mounting plate, wherein the slide plate is slidable between a closed position and an open position, wherein, in the closed position the slide plate blocks material passage from the opening of the top plate to the opening of the bottom plate, wherein, in the open position, the slide plate permits material passage from the opening of the top plate to the opening of the bottom plate.

A slide gate assembly includes a mounting plate with a through opening and an upper surface, and a top plate with a through opening and lower surface, wherein the through opening of the top plate aligns with the through opening of the mounting plate. A slide plate is mounted between the lower surface of the top plate and the upper surface of the mounting plate, wherein the slide plate is slidable between a closed position and an open position, wherein, in the closed position the slide plate blocks material passage from the opening of the top plate to the opening of the bottom plate, wherein, in the open position, the slide plate permits material passage from the opening of the top plate to the opening of the bottom plate.

Method and equipment for conditioning wet concrete (703), the wet concrete (703) being agitated in a revolving-drum concrete mixer (702), thereby bringing changing portions of the wet concrete (703) to a free surface (706) of the wet concrete (703) inside the mixer (702), the agitated wet concrete (703) being cooled and partially carbonated in that liquid and/or solid carbon dioxide is supplied to the concrete mixer (702) simultaneously with liquid nitrogen so that both the supplied nitrogen and the supplied carbon dioxide contact the free surface (706) of the wet concrete (703).

Method and equipment for conditioning wet concrete (703), the wet concrete (703) being agitated in a revolving-drum concrete mixer (702), thereby bringing changing portions of the wet concrete (703) to a free surface (706) of the wet concrete (703) inside the mixer (702), the agitated wet concrete (703) being cooled and partially carbonated in that liquid and/or solid carbon dioxide is supplied to the concrete mixer (702) simultaneously with liquid nitrogen so that both the supplied nitrogen and the supplied carbon dioxide contact the free surface (706) of the wet concrete (703).

A stirring apparatus for foods includes an endless conveyer, a plurality of cups, and a rotation mechanism. The endless conveyer has a conveying surface circulating in an endless manner and is arranged to be inclined. The cups are attached to the endless conveyer to be perpendicular to the conveying surface. The rotation mechanism rotates the cups. The rotation mechanism includes a rotation shaft, a driven magnet, a driving magnet, and a rotation driving device. One end of the rotation shaft is fixed to a bottom plate of the cup. The driven magnet is provided at the other end of the rotation shaft. The driving magnet faces the driven magnet at a predetermined interval. The rotation driving device rotates the driving magnet.

A process for making an oligonucleotide, the process including reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position and inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel.