A microfluidic mixing device comprising two bellows pumps (105, 115), microfluidic cartridges comprising the same and methods for use of the same are provided. The disclosed device enables efficient mixing of samples at the microfluidic scale. More particularly, the microfluidic mixing device comprises: a first bellows pump (105); a second bellows pump (115); a first microchannel fluidly interconnecting the first bellows pump (105) with a sample inlet and a reagent reservoir, wherein the first microchannel comprises a valve (V10) interposed between the pump and the inlet, and a valve (V1) interposed between the pump and the reservoir; a second microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump (115), wherein the second micro channel comprises a valve (V11) interposed between the first and second pump; a third microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump, wherein the third micro channel comprises a valve (V11) interposed between the first and second pump; a first and second pneumatic member pneumatically connected to the first and second bellows pumps; wherein, the volume of the second bellows pump (115) is greater than the volume of the first bellows pump (105).

The present disclosure relates to a pre-5.sup.th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4.sup.th-Generation (4G) communication system such as Long Term Evolution (LTE). A method for operating a terminal in a wireless communication system includes receiving configuration information regarding a random access channel (RACH) from a base station, and transmitting a RACH preamble based on the configuration information. The configuration information includes information indicating the number of RACH transmission occasions in a frequency axis. A terminal includes a processor configured to receive configuration information regarding a RACH from a base station, and transmit a RACH preamble according to the configuration information, wherein the configuration information includes information indicating the number of RACH transmission occasions in a frequency axis.

Apparatus for mixing polymer, the apparatus comprising (i) a mixer housing including an internal chamber, said internal chamber having first and second sections in fluid communication with each other through a passageway; (ii) a first ram received in said first section; and (iii) a second ram received in said second section, where the apparatus is adapted to receive a composition including polymer within said internal chamber and move said composition between said first and second chambers through said passageway by operation of said first and second rams.

Apparatus for mixing polymer, the apparatus comprising (i) a mixer housing including an internal chamber, said internal chamber having first and second sections in fluid communication with each other through a passageway; (ii) a first ram received in said first section; and (iii) a second ram received in said second section, where the apparatus is adapted to receive a composition including polymer within said internal chamber and move said composition between said first and second chambers through said passageway by operation of said first and second rams.

Methods are provided for separating magnetically responsive beads from a droplet in a droplet actuator. Droplet operations electrodes and a magnet are arranged in a droplet actuator to manipulate a bead-containing droplet and position it relative to a magnetic field region that attracts the magnetically responsive beads. The droplet operations electrodes are operated to control the droplet shape and transport it away from the magnetic field region to form a concentration of beads in the droplet. The continued transport of the droplet away from the magnetic field causes the concentration of beads to break away from the droplet to yield a small, concentrated bead-containing droplet immobilized by the magnet.

Methods are provided for separating magnetically responsive beads from a droplet in a droplet actuator. Droplet operations electrodes and a magnet are arranged in a droplet actuator to manipulate a bead-containing droplet and position it relative to a magnetic field region that attracts the magnetically responsive beads. The droplet operations electrodes are operated to control the droplet shape and transport it away from the magnetic field region to form a concentration of beads in the droplet. The continued transport of the droplet away from the magnetic field causes the concentration of beads to break away from the droplet to yield a small, concentrated bead-containing droplet immobilized by the magnet.

An apparatus to realize personalized cosmetic compositions including a formula supply assembly having a plurality of additive reservoirs that contains a plurality of additive substances, a plurality of additive pumps that supplies selected additive quantities of the plurality of additive substances, a base reservoir that contains a base substance, and a base pump that supplies a base quantity of the base substance and a mixing assembly having an additive inlet that receives the selected additive quantities, a base inlet that receives the base quantity, and a mixing channel that mixes the additive quantities with the base quantity to form the personalized cosmetic compositions.

An apparatus to realize personalized cosmetic compositions including a formula supply assembly having a plurality of additive reservoirs that contains a plurality of additive substances, a plurality of additive pumps that supplies selected additive quantities of the plurality of additive substances, a base reservoir that contains a base substance, and a base pump that supplies a base quantity of the base substance and a mixing assembly having an additive inlet that receives the selected additive quantities, a base inlet that receives the base quantity, and a mixing channel that mixes the additive quantities with the base quantity to form the personalized cosmetic compositions.

In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.

In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.