A device for homogenizing a multicomponent fluid including a main channel, a first and a second buffer channels, a collector connected to the main channel with a main conduct, to the first buffer channel with a first fiber and to the second buffer channel with a second fiber. The collector further includes a flow separation point aimed at dividing the main conduct into the first and second fibers, a pumping unit configured to move the multicomponent fluid from the main channel to the first or the second buffer channels through the collector and move the multicomponent fluid from the first or the second buffer channels to the main channel through the collector.

A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.

A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.

The present disclosure relates to a pre-5.sup.th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4.sup.th-Generation (4G) communication system such as Long Term Evolution (LTE). A method for operating a terminal in a wireless communication system includes receiving configuration information regarding a random access channel (RACH) from a base station, and transmitting a RACH preamble based on the configuration information. The configuration information includes information indicating the number of RACH transmission occasions in a frequency axis. A terminal includes a processor configured to receive configuration information regarding a RACH from a base station, and transmit a RACH preamble according to the configuration information, wherein the configuration information includes information indicating the number of RACH transmission occasions in a frequency axis.

The present disclosure relates to a pre-5.sup.th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4.sup.th-Generation (4G) communication system such as Long Term Evolution (LTE). A method for operating a terminal in a wireless communication system includes receiving configuration information regarding a random access channel (RACH) from a base station, and transmitting a RACH preamble based on the configuration information. The configuration information includes information indicating the number of RACH transmission occasions in a frequency axis. A terminal includes a processor configured to receive configuration information regarding a RACH from a base station, and transmit a RACH preamble according to the configuration information, wherein the configuration information includes information indicating the number of RACH transmission occasions in a frequency axis.

Methods are provided for separating magnetically responsive beads from a droplet in a droplet actuator. Droplet operations electrodes and a magnet are arranged in a droplet actuator to manipulate a bead-containing droplet and position it relative to a magnetic field region that attracts the magnetically responsive beads. The droplet operations electrodes are operated to control the droplet shape and transport it away from the magnetic field region to form a concentration of beads in the droplet. The continued transport of the droplet away from the magnetic field causes the concentration of beads to break away from the droplet to yield a small, concentrated bead-containing droplet immobilized by the magnet.

Methods are provided for separating magnetically responsive beads from a droplet in a droplet actuator. Droplet operations electrodes and a magnet are arranged in a droplet actuator to manipulate a bead-containing droplet and position it relative to a magnetic field region that attracts the magnetically responsive beads. The droplet operations electrodes are operated to control the droplet shape and transport it away from the magnetic field region to form a concentration of beads in the droplet. The continued transport of the droplet away from the magnetic field causes the concentration of beads to break away from the droplet to yield a small, concentrated bead-containing droplet immobilized by the magnet.

A mixing device and method for generating reaction plastic, the mixing device including: a mixing chamber configured to mix reactive components to generate the reaction plastic; a discharge unit, including a discharge pipe connected to the mixing chamber configured to discharge the reaction plastic generated in the mixing chamber; a cleaning piston that is axially aligned with the discharge pipe of the discharge unit and is moveable into the discharge pipe to clean reaction plastic from the discharge pipe; a fluid supply device configured to provide a lubricant into the discharge unit via an outlet to lubricate the discharge unit, a control piston arranged within the mixing chamber and configured to control flow of the reactive components; wherein an axial direction of the control piston is oblique to an axial direction of a discharge pipe of the discharge unit.

A mixing device and method for generating reaction plastic, the mixing device including: a mixing chamber configured to mix reactive components to generate the reaction plastic; a discharge unit, including a discharge pipe connected to the mixing chamber configured to discharge the reaction plastic generated in the mixing chamber; a cleaning piston that is axially aligned with the discharge pipe of the discharge unit and is moveable into the discharge pipe to clean reaction plastic from the discharge pipe; a fluid supply device configured to provide a lubricant into the discharge unit via an outlet to lubricate the discharge unit, a control piston arranged within the mixing chamber and configured to control flow of the reactive components; wherein an axial direction of the control piston is oblique to an axial direction of a discharge pipe of the discharge unit.

A microfluidic mixing device comprising two bellows pumps (105, 115), microfluidic cartridges comprising the same and methods for use of the same are provided. The disclosed device enables efficient mixing of samples at the microfluidic scale. More particularly, the microfluidic mixing device comprises: a first bellows pump (105); a second bellows pump (115); a first microchannel fluidly interconnecting the first bellows pump (105) with a sample inlet and a reagent reservoir, wherein the first microchannel comprises a valve (V10) interposed between the pump and the inlet, and a valve (V1) interposed between the pump and the reservoir; a second microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump (115), wherein the second micro channel comprises a valve (V11) interposed between the first and second pump; a third microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump, wherein the third micro channel comprises a valve (V11) interposed between the first and second pump; a first and second pneumatic member pneumatically connected to the first and second bellows pumps; wherein, the volume of the second bellows pump (115) is greater than the volume of the first bellows pump (105).