The manufacturing apparatus includes a first capsule containing a first formulation; a second capsule containing a second formulation; a receiving device configured to receive the first and second capsules; a mixing machine including a receiving housing configured to receive the receiving device equipped with the first and second capsules, and a control unit configured to control the operation of the mixing machine; and a detection device configured to detect the presence of the receiving device in the receiving housing.

Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.

Well material distribution methods may include gravity feeding bulk well materials including at least one well material component into a mixing vessel which may include a mixing vessel interior and at least one mixing device disposed in the mixing vessel interior; forming a well material mixture by mixing the bulk well materials including at least one well material component in the mixing vessel interior of the mixing vessel via operation of the at least one mixing device; distributing the well material mixture from the mixing vessel interior of the mixing vessel to at least one mud pit; and distributing a substantially homogenous well material mixture from the at least one mud pit to a hydrocarbon well.

A truffle configured cosmetic article which includes a protective outer shell, an inner volume of cosmetic and a capsule positioned in the cosmetic containing active ingredients. An appliance is adapted to receive the article, heat and blend the article to produce a warm skin formulation which can be applied by the user. The article is produced with the use of a mold. A combination of wax and coconut oil is melted and applied to most of the interior surface of the mold, defining a volume into which a cosmetic is applied as well as a capsule additive. The article is then sealed with additional wax and coconut oil material. The article is then released and ready for use in the appliance or to be wrapped.

A device and method for producing a bone cement paste from a monomer liquid and a cement powder, wherein the device comprises a cartridge with a cylindrical interior chamber for mixing the parent components, whereby the interior chamber of the cartridge is closed on the front side up to a delivery opening for expelling the bone cement paste from the interior chamber, a delivery plunger which is arranged in the interior chamber of the cartridge and which is supported in a linearly movable manner in the direction of the delivery opening, the cement powder, which is arranged in the interior chamber of the cartridge between the delivery opening and the delivery plunger, a monomer receptacle with an interior chamber in which a monomer liquid container containing the monomer liquid is contained, whereby in the monomer receptacle, a conveying plunger is arranged movable in the longitudinal direction of the monomer receptacle, a compressed gas connection, whereby the conveying plunger is arranged between the monomer liquid container and the compressed gas connection or the compressed gas line in the monomer receptacle.

An apparatus for producing a composition includes a holding device for holding first and second capsules including first and second deformable compartments, respectively, which contain a first formulation and a second formulation, respectively; a first compression element including a first compression surface designed to apply a pressure to the first deformable compartment of the first capsule; and a second compression element including a second compression surface designed to apply a pressure to the second deformable compartment of the second capsule. The first compression surface is designed to conduct and guide the contents of the first capsule to a first passage in the first capsule that can be fluidically connected to the first deformable compartment and the second compression surface is designed to conduct and guide the contents of the second capsule to a second passage in the second capsule that can be fluidically connected to the second deformable compartment.

A carbonated beverage maker includes a water reservoir, a carbon dioxide creation chamber, and a carbonation chamber. The water reservoir holds ice water and has a first impeller and a shroud surrounding the first impeller. The carbon dioxide creation chamber contains chemical elements and receives warm water. The chemical elements react with each other to create carbon dioxide when the warm water is introduced to the carbon dioxide creation chamber. The carbonation chamber is connected to the water reservoir and the carbon dioxide creation chamber. The carbonation chamber has a second impeller that includes a stem portion and blades. The stem portion and the blades define conduits therein. The blades create a low pressure region in a lower portion of the carbonation chamber such that carbon dioxide from the carbon dioxide creation chamber flows through the conduits to the low pressure region.

A manufacturing apparatus including a first capsule containing a predetermined amount of a first formulation, and a second capsule containing a predetermined amount of a second formulation, the first and second capsules being distinct from each other; a receiving device configured to receive the first and second capsules; and a mixing machine configured to receive the receiving device equipped with the first and second capsules, and to mix the first and second formulations contained in the first and second capsules so as to obtain the cosmetic product.

A production apparatus includes a receiving device designed to receive a first and a second capsule containing a first and a second formulation, respectively, the receiving device being designed to be in an open position in which the first and the second capsule can be introduced into the receiving device and a closed position in which the receiving device holds the first and second capsules in position, the receiving device further being designed in such a way that when the receiving device holding the first and second capsules is moved from the open position to the closed position, the first and second capsules are connected; the apparatus further includes a mixing machine designed to receive the receiving device holding the first and second capsules, and to mix the first and second formulations contained in the first and second capsules such as to obtain the composition.

The manufacturing apparatus comprises a first capsule containing a predetermined amount of a first formulation, the first capsule including a first connection portion and an outlet passage provided with an outlet orifice; a second capsule containing a predetermined amount of a second formulation, and including a second connection portion configured to be connected to the first connection portion; and a mixing machine configured to receive the first and second capsules, and to mix the first and second formulations contained in the first and second capsules so as to obtain the cosmetic product. The manufacturing apparatus is configured to automatically close the outlet passage when the first and second capsules are received in the mixing machine, and to automatically clear the outlet passage when the first and second capsules are removed out of the mixing machine.