Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.

In drug mixing devices of disclosed embodiments, a main flow path extending from one end configured to allow liquid inside the first container to enter the main flow path therethrough to another end configured to allow liquid inside the second container to enter the main flow path therethrough, and a branch flow path branching from the main flow path are formed. The drug mixing device includes a body including a first connection part configured to be coupled with the first container and a second connection part configured to be coupled with the second container, and a backflow prevention part disposed in a partial flow path of the main flow path extending to the one end with reference to the connection point of the main flow path and the branch flow path, the backflow prevention part being configured to prevent liquid from flowing from the connection point to the one end.

Systems for a plastic pump/actuator capable of containing and pumping organic solvents and lubricants and having a more desirable lubricity within the system. The system has at least two cylinders, with plungers therein, oppositely disposed from each other and configured to operably connect to a pump.

According to one example, a valve for an apparatus configured to mix bone cement is disclosed. The valve can include a base defining a first portion of a passage. The passage can be configured to allow a component of the bone cement through the valve. The valve can include a projection extending from the base to a base opposing end and forming a second portion of the passage that communicates with the first portion. The projection can have a frustoconically shaped surface that comprises one of an outer surface or an inner surface that forms a part of the second portion of the passage.

The invention relates to a mixing capsule (1) comprising a first chamber (2) to receive a composition A and a second chamber (3) to receive a composition B, characterised in that the first chamber (2) and the second chamber (3) are arranged rotatably about the longitudinal axis (5) of the mixing capsule (1), the first chamber (2) comprising a first opening (25), the second chamber (3) comprising a second opening (26), the first opening (25) and the second opening (26) being arranged perpendicularly to the longitudinal axis (5) and plan-parallelly to each other and/or perpendicularly spaced, the first opening (25) and the second opening (26) being arranged incongruently to each other in a storage position (4), the first opening (25) and the second opening (26) being arranged congruently to each other in a handling position (6). Furthermore, the invention relates to a method for mixing at least two compositions A and B to a composition C in a mixing capsule and to a use of the mixing capsule.

Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.

One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder as parent components of the bone cement paste and for delivering the mixed bone cement paste, the device having a cartridge having a cylindrical interior. The interior of the cartridge is closed on the front side except for a delivery opening for expelling the bone cement paste. A delivery plunger is arranged in the interior of the cartridge. The cement powder is arranged in the interior of the cartridge. A closure is arranged on the front side of the delivery plunger. The closure closes the delivery opening when the delivery plunger is pressed against the front side of the interior of the cartridge. The closure blocks a further movement of the delivery plunger so that the delivery plunger is spaced from the front side of the interior of the cartridge at least in some areas and a dead volume remains in the interior of the cartridge when the delivery plunger is pressed against the front side of the interior of the cartridge.

The invention relates to a mixing capsule (1) comprising a first chamber (2) to receive a composition A and a second chamber (3) to receive a composition B, characterised in that the first chamber (2) and the second chamber (3) are arranged rotatably about the longitudinal axis (5) of the mixing capsule (1), the first chamber (2) comprising a first opening (25), the second chamber (3) comprising a second opening (26), the first opening (25) and the second opening (26) being arranged perpendicularly to the longitudinal axis (5) and plan-parallelly to each other and/or perpendicularly spaced, the first opening (25) and the second opening (26) being arranged incongruently to each other in a storage position (4), the first opening (25) and the second opening (26) being arranged congruently to each other in a handling position (6). Furthermore, the invention relates to a method for mixing at least two compositions A and B to a composition C in a mixing capsule and to a use of the mixing capsule.

Described herein is a baby bottle formula mixing and feeding assembly designed to be coupled to a standard baby feeding bottle or powder mixing bottle. The formula mixing assembly is designed to include at least four main components: a bottom housing, a cylindrical gate body, a top housing and a cylindrical pliable cup body disposed within the top/bottom housing. A locking mechanism is included that unlocks the top housing and the gate body containing the pliable cup body and the formula, such that the apertures in the gate body align with the apertures in the bottom housing to when the top housing is rotated so as to empty the formula contents into the bottle with the liquid. e both the bottom housing and the gate body.

A blender system includes a bottle, a display, and a container for blending ingredients from a container with a fluid. The bottle includes a blending chamber with an opening to receive a fluid and a shoulder about the opening. The lid is configured to couple with the bottle and includes a container receiver. The container receiver is configured to receive the container and position a lip of the container against the shoulder when the lid is coupled to the bottle. The container receiver is further configured to press the container towards the opening while the shoulder holds the lip stationary to discharge the ingredients from the container into the fluid in the blending chamber. The display displays information regarding the blender system.