The present disclosure relates to a dialysis apparatus comprising a membrane having at least one protein from the lipocalin family bound thereon. The disclosure further relates to methods of removing non-polar, hydrophobic and/or protein bound uremic toxins from a target subject utilizing the dialysis apparatus described herein as well as methods of extracorporeal detoxification.

Disclosed are methods for critical point drying a composite material. After exposing the composite material to a supercritical fluid, the composite material dries as the supercritical fluid evaporates with reduced pressure. The composite materials are useful as chromatographic separation media.

A product having powder-like properties, the product comprising animal fibres, e.g. wool, having a length less than 10 mm, preferably less than about 3 mm, more preferably less than about 2 mm. Surprisingly, animal fibres having a length below a certain fibre length have powder-like properties, such as improved rheological properties, increased density, increased surface area and increased porosity. Also described are processes for preparing compositions and composites thereof, and uses thereof, e.g., as a filter aid, in a dietary supplement, in a filler and in a hair thickener.

The present invention relates to the field of water treatment/fluoride removal and to materials/devices useful in such processes. Specifically, the invention provides for hybrid materials comprising amyloid fibrils and ZrO2; and to composite materials further comprising a support material. The invention further provides for the treatment of water using such hybrid or composite materials.

The present invention relates to a method of making a porous sponge-like formulation that can well absorb water, oil and organic solvents separately or combined. Methods of preparing said formulation and its use in medical, pharmaceutical, biotechnological, chemical as well as in wound care, home care, (agro-)environmental and construction material applications are also provided.

The present disclosure relates to a dialysis apparatus comprising a membrane having at least one protein from the lipocalin family bound thereon. The disclosure further relates to methods of removing non-polar, hydrophobic and/or protein bound uremic toxins from a target subject utilizing the dialysis apparatus described herein as well as methods of extracorporeal detoxification.

Disclosed is a separation material comprising hydrophobic polymer particles and a coating layer covering at least a portion of a surface of the hydrophobic polymer particles, wherein the coating layer comprises a hydrophilic polymer having hydroxy groups, and the hydrophilic polymer has a group represented by NHR-L or an epoxy group, wherein R represents a hydrocarbon group and L represents a carboxy group or an amino group.

The present disclosure relates to a dialysis apparatus comprising a membrane having at least one protein from the lipocalin family bound thereon. The disclosure further relates to methods of removing non-polar, hydrophobic and/or protein bound uremic toxins from a target subject utilizing the dialysis apparatus described herein as well as methods of extracorporeal detoxification.

An object of the present invention is to provide a technique to create novel engineered protein ligands that, when immobilized through a lysine residue (its side chain -amino group) which allows for efficient immobilization to a carrier, show the optimum binding capacity and binding efficiency to a target molecule. The present invention provides an engineered protein having a sequence obtained by replacing all the lysine residues in Protein A, which is the most typical protein ligand, with other amino acids, and adding lysine at a terminal; and an affinity separation matrix in which such an engineered protein is immobilized on a water-insoluble carrier by reductive amination or the like. This affinity separation matrix is characterized by its high binding capacity to a target molecule even when the immobilized amount of the ligand is small.

The present disclosure relates to a dialysis apparatus comprising a membrane having at least one protein from the lipocalin family bound thereon. The disclosure further relates to methods of removing non-polar, hydrophobic and/or protein bound uremic toxins from a target subject utilizing the dialysis apparatus described herein as well as methods of extracorporeal detoxification.