Disclosed are processes and intermediates for the preparation of compound (X), which is currently being investigated for the treatment of prostate cancer.

##STR00001##

Described herein are methods and devices that allow the generation of [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides (such as [F-18]tosyl fluoride) in a manner that is suitable for radiosynthesis of F-18 labeled radiopharmaceuticals using currently available synthesis modules.

In one embodiment, a continuous process for preparing organic carbonate solvent of Formula (I) as described herein comprises contacting a first reactant (an alcohol) with a reactive carbonyl source (carbonyldiimidazole (CDI) or an alkylchloroformate) in the presence of a catalyst in reaction stream flowing through a continuous flow reactor at temperature 20° C. to about 160° C. and at a flow rate providing a residence time in the range of about 0.1 minute to about 24 hours; collecting a reactor effluent exiting from the continuous flow reactor; recovering a crude product from the reactor effluent; and distilling the crude product to obtain the organic carbonate compound of Formula (I). In another embodiment, the first reactant is an epoxide and the carbonyl source is carbon dioxide.

The present invention relates to cyclododecanone and a preparation method therefor. According to the present invention, a cyclododecanone preparation method capable of achieving a high conversion rate and minimizing unreacted materials and the production of reaction byproducts can be provided. In addition, the present invention implements a high conversion rate and selectivity despite a simplified process, and thus can be helpfully utilized in economical laurolactam production methods that are easy to mass-produce commercially. According to the present invention, the proportions of cyclododecanol, cyclododecadiol, and the like, obtained as reaction byproducts, in the final product can be drastically reduced, and cyclododecanone can be produced at a high conversion rate.

A microencapsulated polyaddition catalyst comprises a capsule core, containing polyaddition catalyst, and an acrylic copolymer capsule shell, the acrylic copolymer comprising copolymerized units of an intermolecular anhydride of an ethylenically unsaturated C.sub.3-C.sub.12 carboxylic acid. The polyaddition catalyst is selected from acyclic tertiary amines, alicyclic tertiary amines, N-alkylimidazoles, phosphines and organic metal salts. It is suitable for catalysing the reaction of a polyol compound with a polyisocyanate compound. The polyaddition catalyst is released by a chemical stimulus, such as on contact with polyols or water, for example.

A highly active hydroprocessing catalyst that comprises a doped support having been impregnated with a metal-impregnation solution, comprising a complexing agent and a hydrogenation metal, and filled with an organic additive blend. The catalyst is made by providing a doped support particle followed by impregnating the doped support particle with a metal impregnation solution that contains both a hydrogenation metal component and a complexing agent component to provide a metal-impregnated doped support particle. The metal-impregnated doped support particle is dried, but not calcined, and impregnated with an organic additive blend component.

The present invention relates to catalyst composition for cyclic carbonate production from CO.sub.2 and olefins using halohydrin agent as the co-reactant under mild conditions, which can effectively catalyze the cyclic carbonate synthesis and provides good selectivity to cyclic carbonate, wherein said catalyst composition comprising: a) the metal complex as shown in structure (I):

##STR00001## wherein, M represents transition metal atom; R.sub.1, R.sub.2, and R.sub.3 represent independent group selected from hydrogen atom, halogen atom, alkyl group, alkenyl group, alkynyl group, alkoxy group, amine group, phenyl group, benzyl group, cyclic hydrocarbon group comprising hetero atom, perfluoroalkyl group, or nitro group; R.sub.4 represents group selected from alkylene group, cycloalkylene group, or phenylene group; X represents group selected from halogen atom, acetate group, or triflate group; b) the halohydrin agent in at least one solvent; and c) at least one base.

This organopolysiloxane having a structural unit represented by general formula (1):

##STR00001##

(in the formula, R.sup.1 represents an unsubstituted or substituted alkyl group having 1-12 carbon atoms or an unsubstituted or substituted aryl group having 6-10 carbon atoms) and having at least one group that directly binds to a silicon atom and that is selected from the groups represented by general formula (2);

R.sup.2O—  (2)

(in the formula, R.sup.2 represents a hydrogen atom, an unsubstituted or substituted alkyl group having 1-10 carbon atoms, or an unsubstituted or substituted aryl group having 6-10 carbon atoms), is capable of achieving both hardness and bending resistance, exhibits excellent fast curing ability even when an amine-based compound is used as a curing catalyst, and is highly safe.

The present disclosure provides a quantum-dot ligand, a quantum-dot catalyst and a quantum-dot device. The quantum-dot ligand includes: a first ligand having a first group and a second group and a second ligand having an inorganic ion, in which a coordination bond is formed between the first group and a surface of a quantum dot, a hydrogen bond is formed between the second group and a hydroxyl group; and a coordination bond is formed between the inorganic ion and the surface of the quantum dot. The quantum-dot catalyst of the present disclosure can enhance a catalytic activity of the quantum dots and improve the catalytic performance.

The present invention relates to catalyst composition for cyclic carbonate production from CO.sub.2 and epoxides under mild conditions, which can effectively catalyze the cyclic carbonate synthesis and provides good selectivity to cyclic carbonate, wherein said catalyst composition comprising: a) the metal complex as shown in structure (I):

##STR00001## wherein, M represents transition metal atom; R.sub.1, R.sub.2, and R.sub.3 represent independent group selected from hydrogen atom, halogen atom, alkyl group, alkenyl group, alkynyl group, alkoxy group, amine group, phenyl group, benzyl group, cyclic hydrocarbon group comprising hetero atom, perfluoroalkyl group, or nitro group; R.sub.4 represents group selected from alkylene group, cycloalkylene group, or phenylene group; X represents group selected from hydrogen atom, acetate group, or triflate group; and b) the organic compound as the co-catalyst selected from compound containing nitrogen, compound of quaternary ammonium salts, or compound of iminium salts.