In some aspects, the present disclosure provides pharmaceutical compositions comprising a) a therapeutic agent; b) a metal-organic framework (MOF) or a coordination polymer; and c) a pharmaceutically acceptable polymer; wherein the therapeutic agent is encapsulated within the metal-organic framework or coordination polymer to form an encapsulated therapeutic agent, and wherein the encapsulated therapeutic agent is further encapsulated, entrapped, embedded, dispersed within, or complexed to the pharmaceutically acceptable polymer. The present disclosure also provides methods of making said compositions, methods of treating a disease or disorder comprising administering to a subject said compositions. The present disclosure also provides microneedles and implantable medical devices comprising said compositions.

A hydrolysable mixture M contains a) at least one compound A with at least one hydrogen atom directly bonded to a silicon atom, b) at least one compound B that contains at least one carbon-carbon multiple bond, c) at least one hydrosilylation catalyst, and d) at least one strong electron donor, as a catalyst additive.

A method of manufacturing a catalyst article, the method comprising: providing a complex of a maleic acid-containing polymer and a PGM; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.

A transition metal-based heterogeneous carbonylation reaction catalyst has an excellent catalytic activity and selectivity in the carbonylation reaction and is easily separated from a product, by crosslinking polymerizing a transition metal-based homogeneous catalyst unit through a Friedel-Craft reaction. The catalyst may be used in a method for preparing lactone. The transition metal-based heterogeneous carbonylation reaction catalyst allows to produce lactone or succinic anhydride with an epoxide compound while showing a high selectivity, and can be applied in industrial very usefully due to easy separation from the product and thus reusing thereof.

A metal organic framework comprising zinc (II) ions and second metal ions, such as iron (II) ions, cobalt (II) ions, and copper (II) ions as nodes or clusters and coordinated 1,3,5-benzenetricarboxylic acid struts or linkers between them forming a porous coordination network in the form of polyhedral crystals that are isostructural to HKUST-1. Transmetallation processes for producing the metal organic frameworks, as well as methods for applications of the metal organic frameworks as catalysts, specifically catalysts for the oxidation of cyclic hydrocarbons, such as toluene, cyclohexane, and methylcyclohexane.

Described herein are multi-functionalized hollow fiber organocatalysts, processes for producing multi-functionalized hollow fiber organocatalysts, and processes that utilize multi-functionalized hollow fiber organocatalysts for reacting chemicals. A variety of chemical reactions may be enhanced with the multifunctional hollow fiber organocatalysts. The multi-functionalized hollow fiber organocatalysts are particularly advantageous when used as heterogeneous organocatalysts and continuous-flow reactors.

An adhesive composition including a reaction mixture of: (A) at least one isocyanate-containing compound; (B) at least one polyol compound; and (C) a copolymerized crystalline latent catalyst; a process for making the above adhesive composition; and a laminate structure made using the above adhesive composition.

According to one embodiment, a catalyst system that reduces polymeric fouling may comprise at least one titanate compound, at least one aluminum compound, and at least one antifouling agent or a derivative thereof. The antifouling agent may comprise a structure comprising a central aluminum molecule bound to an R1 group, bound to an R2 group, and bound to an R3 group. One or more of the chemical groups R1, R2, and R3 may be antifouling groups comprising the structure —O((CH.sub.2).sub.nO).sub.mR4, where n is an integer from 1 to 20, m is an integer from 1 to 100, and R4 is a hydrocarbyl group. The chemical groups R1, R2, or R3 that do not comprise the antifouling group, if any, may be hydrocarbyl groups.

A method for preparing formamide compounds via hydrogenation of carbon dioxide catalyzed by porous materials includes the following steps: by taking porous organometallic polymers as catalysts, reacting amine compounds with carbon dioxide and hydrogen under an air atmosphere to prepare formamide compounds. The method has the advantages of high reaction efficiency, good selectivity, mild conditions, economy, environmental protection, and simple operation. The catalysts are solid organometallic polymers with large specific surface area, strong carbon dioxide adsorption, hierarchical pore distribution, and uniformly dispersed metal centers. They are designed and synthesized as the reaction catalysts by changing the proportion of the cross-linked comonomer. The catalysts can be especially used for catalytic synthesis of fine chemical N, N-dimethylformamide (DMF) without addition of any additional solvent, alkali, or other additives, which is convenient for separation and purification of DMF.

Proton-conducting, fluorinated polymer grafted particles for use in the preparation of catalytic layers for fuel cells, such as H.sub.2/air cells or H.sub.2/O.sub.2 cells. The grafted particles include a particle made of a material for catalyzing oxygen reduction or hydrogen oxidation, such as a platinum particle, that has been grafted with a proton-conducting, fluorinated polymer graft. The proton-conducting, fluorinated polymer graft includes an organic spacer group, a single bond or an organic spacer group, a repeating unit resulting from polymerization of a fluorinated styrenic monomer, and a repeating unit resulting, from polymerization of a non-fluorinated styrenic monomer bearing at least one proton-conducting group.