B01L2200/0615

Pipette-fillable cartridge

A pipette-fillable fluid reservoir body. The fluid reservoir body includes two or more discrete fluid chambers therein. At least one of the fluid chambers contains a pressure compensation device and at least another one of the fluid chambers is devoid of a pressure compensation device. Each of the fluid chambers is in fluid flow communication with a fluid supply via, and each of the fluid chambers have sidewalls and a bottom wall attached to the side walls, wherein the bottom wall slopes toward the fluid supply via. The fluid reservoir body also includes an ejection head support face in fluid flow communication with the fluid chambers for attachment of a fluid ejection device to the ejection head support face for ejecting fluid from the fluid chambers.

Liquid dispenser for a bottle

Liquid dispensers for bottles comprise a dispensing chamber having small portals at either end. Dropwise addition of flavoring or coloring liquids, such as vermouth or bitters, to alcoholic beverages using those liquid dispensers is also disclosed.

SPECIMEN COLLECTION RECEPTACLE
20230095562 · 2023-03-30 ·

A fluid specimen collection receptacle includes a cup containing a chamber and an open end and a lid for connection with the cup open end and closing the cup chamber. A closure and a specimen collection needle are connected with the lid and a reservoir is arranged beneath the lid and connected with the closure for rotation relative to the lid between open and closed positions. The closure affords access to the needle when the closure is in the open position and prevents access to the needle when the closure is in the closed position. The reservoir includes a chamber closed by a portion of the lid when the closure is in the open position. When the closure is rotated to the closed position, the reservoir is opened for communication with the cup chamber to release an absorbent material from the reservoir chamber into the cup chamber to solidify any residual fluid specimen within the cup chamber.

Microfluidic cartridge for processing and detecting nucleic acids

A system, configured to facilitate processing and detection of nucleic acids, the system comprising a process fluid container and a cartridge comprising: a top layer, a set of sample port-reagent port pairs, a shared fluid port, a vent region, a heating region, and a set of detection chambers; an intermediate substrate, coupled to the top layer comprising a waste chamber; an elastomeric layer, partially situated on the intermediate substrate; and a set of fluidic pathways, each formed by at least a portion of the top layer and a portion of the elastomeric layer, wherein each fluidic pathway is fluidically coupled to a sample port-reagent port pair, the shared fluid port, and a detection chamber, comprises a portion passing through the heating region, and is configured to be occluded upon deformation of the elastomeric layer, to transfer a waste fluid to the waste chamber, and to pass through the vent region.

DEVICES AND METHODS FOR LOADING OF FLUIDIC RECEPTACLES

Aspects of this disclosure relate to systems, devices, and methods for the transfer of fluid to fluidic receptacles. In some embodiments, the fluid contains one or more molecules (e.g., one or more peptides, proteins, and/or nucleic acids) of interest, and the fluidic receptacle includes an integrated device. In certain embodiments, the one or more molecules can be immobilized on the integrated device for subsequent analysis (e.g., sequencing). Certain aspects of the present disclosure are directed towards systems and methods that can, in some instances, enhance the immobilization of the one or more molecules on the integrated device, e.g., by improving a rate of sample interaction with the integrated device. Through the use of systems, devices, and methods of the instant disclosure, target molecules may be more readily sequenced or prepared for sequencing. For example, in some embodiments, systems, devices, and methods of the instant disclosure allow automated loading of the fluidic receptacle using a fluidic device.

FOLDABLE TEST TUBE RACK
20230128887 · 2023-04-27 ·

The application is related to a test tube rack, and the test tube rack comprises a first supporting surface and a second supporting surface. The test tube rack further comprises a first hole used for inserting a test tube. The first supporting surface and the second supporting surface can be folded. Such test tube rack can be subject to folding shrink packaging when being packaged and is opened when being used, so that a test tube is inserted to operate.

Separable cassette for measuring glycated hemoglobin

The present invention relates to a separable cassette for measuring glycated hemoglobin. It is easy to use the separable cassette for measuring glycated hemoglobin of the present invention since a reagent is sequentially leaked during the rotation thereof. In addition, there is no need to shake the reagent beforehand, as the reagent without residual reagent is fully discharged by the rotation. Therefore, the measurement result is accurate because an error between the amount of the reagent used and the amount of sample blood is small.

PIPETTE TIP WITH TWO POSITIVE ANGLE STEPS
20230064079 · 2023-03-02 · ·

A pipette includes an end section, a first section, a second section and a third section aligned along a central axis of the pipette tip. The end section comprises an orifice for aspirating and dispensing a fluid. A first kink is formed in an inner surface of the pipette tip between the first section and the second section, such that an angle between the inner surface of the first section and the central axis is smaller than an angle between the inner surface of the second section and the central axis. A second kink is formed in the inner surface of the pipette tip between the second section and the third section, such that the angle between the inner surface of the second section and the central axis is smaller than an angle between the inner surface of the third section and the central axis.

System and method for processing and detecting nucleic acids

A system and method for processing and detecting nucleic acids from a set of biological samples, comprising: a capture plate and a capture plate module configured to facilitate binding of nucleic acids within the set of biological samples to magnetic beads; a molecular diagnostic module configured to receive nucleic acids bound to magnetic beads, isolate nucleic acids, and analyze nucleic acids, comprising a cartridge receiving module, a heating/cooling subsystem and a magnet configured to facilitate isolation of nucleic acids, a valve actuation subsystem configured to control fluid flow through a microfluidic cartridge for processing nucleic acids, and an optical subsystem for analysis of nucleic acids; a fluid handling system configured to deliver samples and reagents to components of the system to facilitate molecular diagnostic protocols; and an assay strip configured to combine nucleic acid samples with molecular diagnostic reagents for analysis of nucleic acids.

Centrifugal smearing device and sealed rotating container

The present invention addresses the problem of providing a centrifugal smearing device and a sealed rotating container in which liquid components do not leak to an outside of the sealed rotating container. To solve this problem, in a centrifugal smearing device (30) including a sealed rotating container (34) that houses a chamber (10) with a slide glass removably attached for holding the liquid sample to smear cells in the liquid sample with a centrifugal force onto the slide glass, and a base (31) housing the sealed rotating container (34) and including rotational driving means (32) for rotating the sealed rotating container (34), the sealed rotating container (34) includes a main body (40) capable of housing the chamber (10) and a lid (42) for closing an upper surface opening portion of the main body (40), and has a storage section (46) for storing liquid scattered from the chamber (10) during being centrifuged, formed on an inside face of the main body (40).