B01L2200/0684

CARTRIDGE AND BIOLOGICAL DETECTION SYSTEM
20230050554 · 2023-02-16 · ·

A cartridge is for a detection of a sample or a first component, wherein the sample includes the first component and a second component. The cartridge includes a first injection chamber, a second injection chamber, a separation chamber, a collection chamber and a first detection chamber. The first injection chamber and the second injection chamber are adapted for injecting the sample or the first component. The separation chamber is connected to the first injection chamber, and the sample injected from the first injection chamber is adapted to be separated into the first component and the second component in the separation chamber. The collection chamber is connected to the separation chamber and the second injection chamber. The first detection chamber is connected to the collection chamber. A biological detection system is further provided.

System and method for GMR-based detection of biomarkers

A system for detecting analytes in a test sample, and a method for processing the same, is provided. The system includes a cartridge reader unit that has a control unit and a pneumatic system, and a cartridge assembly that prepares the samples with mixing material(s) through communication channels. The assembly has a memory chip with parameters for preparing the sample and at least one sensor (GMR sensor) for detecting analytes in the sample. The assembly is pneumatically and electronically mated with the reader unit via a pneumatic interface and an electronic interface such that the parameters may be implemented via the control unit. The pneumatic system is contained within the unit and has pump(s) and valve(s) for selectively applying fluid pressure to the pneumatic interface of the assembly, and thus through the communication channels, to move the sample and mixing material(s) through and to sensor. The control unit activates the pneumatic system to prepare the sample and provide it to the sensor for detecting analytes, and also processes measurements from the sensor to generate test results.

Testing for particulates

A method is provided for testing for presence of a particulate selected from the group consisting of: a microorganism, a fungus, a bacteria, a spore, a virus, a mite, a biological cell, a biological antigen, a protein, a protein antigen, and a carbohydrate antigen. The method includes (a) collecting, in a tube (22), fluid that potentially contains the particulate, (b) using a plunger (24) to push the fluid through a filter (26) disposed at a distal portion of the tube or at a distal end of the plunger, and subsequently, (c) while the filter is inside the tube, ascertaining if any of the particulate was trapped by the filter by applying a particulate-presence-testing-facilitation solution to the filter. Other embodiments are also described.

Pipette-fillable cartridge

A pipette-fillable fluid reservoir body. The fluid reservoir body includes two or more discrete fluid chambers therein. At least one of the fluid chambers contains a pressure compensation device and at least another one of the fluid chambers is devoid of a pressure compensation device. Each of the fluid chambers is in fluid flow communication with a fluid supply via, and each of the fluid chambers have sidewalls and a bottom wall attached to the side walls, wherein the bottom wall slopes toward the fluid supply via. The fluid reservoir body also includes an ejection head support face in fluid flow communication with the fluid chambers for attachment of a fluid ejection device to the ejection head support face for ejecting fluid from the fluid chambers.

CUVETTE FOR ANALYSIS OF LIQUIDS
20230041914 · 2023-02-09 · ·

A cuvette for analysis of liquids, including a first cuvette portion and a second cuvette portion, which are joined together, with a cuvette cavity, an inlet passage and an outlet passage being formed between the first cuvette portion and the second cuvette portion, the inlet passage and the outlet passage both in communication with the cuvette cavity, wherein the outlet passage is provided therein with a labyrinth-like sealing structure, which prevents backfill of a gas that has been discharged from the outlet passage during filling of a liquid to be analyzed in the cuvette.

TISSUE HOLDER ASSEMBLY AND COMPONENTS THEREOF
20230012310 · 2023-01-12 ·

A tissue holder cap for covering a tissue holder includes a cover having a perimeter, the cover having an outer surface and an inner surface opposite from the outer surface. The cover includes a central portion having an opening configured for receiving a central post of the tissue holder, a first latch extending from the perimeter of the cover, and a second latch extending from the perimeter of the cover, circumferentially spaced apart from the first latch. The cover also includes a first protrusion configured to engage the post of the tissue holder. When the first protrusion engages with the post, each of the first latch and the second latch automatically aligns with one or more of a plurality of tabs on located on a circumferential sidewall of the tissue holder to thereby securely fasten the tissue holder cap onto the tissue holder.

SYSTEMS AND METHODS FOR FLUID SENSING USING PASSIVE FLOW

Aspects relate to systems and methods for fluid sensing using passive flow. An exemplary system includes a microfluidic device, the microfluidic device including at least a reservoir configured to contain at least a fluid and at least a passive flow component in fluidic communication with the at least a reservoir and configured to flow the at least a fluid with predetermined flow properties, at least an sensor device configured to be in sensed communication with the at least a fluid and detect at least a sensed property; and at least an sensor interface configured to wet at least a surface of the at least a sensor device with the at least a fluid.

Liquid dispenser for a bottle

Liquid dispensers for bottles comprise a dispensing chamber having small portals at either end. Dropwise addition of flavoring or coloring liquids, such as vermouth or bitters, to alcoholic beverages using those liquid dispensers is also disclosed.

NUCLEIC ACID AMPLIFICATION METHOD AND NUCLEIC ACID AMPLIFICATION APPARATUS
20180002737 · 2018-01-04 ·

A nucleic acid amplification method includes a step of heating a first region of a container housing a droplet containing a target nucleic acid and a sample necessary for amplification of the target nucleic acid to a denaturation temperature of the target nucleic acid and heating a second region different from the first region to a synthesis temperature of the target nucleic acid, and an amplification step of repeating a cycle through a denaturation stage at which the droplet housed in the container is moved to and retained in the first region and a synthesis stage at which the droplet is moved to and retained in the second region at a plurality of times. At the amplification step, periods of part of cycles of the plurality of cycles are made shorter than periods of the other cycles.

BIOPSY SAMPLE CONTAINER
20180000463 · 2018-01-04 ·

An apparatus for individually storing multiple tissue samples separately from each other includes a base, a lid, a lock, and one or more vents. The base defines a plurality of reservoirs and a plurality of identification areas. A portion of the base defines an opening corresponding to each reservoir. The lid is configured to secure the multiple tissue samples within a corresponding reservoir by enclosing each corresponding opening in the closed configuration. The lock is configured to selectively lock the lid against the base in the closed configuration. The one or more vents are configured to enable entry of fluid into the reservoirs when the lid is in the closed configuration. The one or more vents are further configured to prevent exit of tissue samples from the reservoirs when the lid is in the closed configuration.