B01L2300/02

Systems for gross processing of tissue samples and related methods

Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.

Self-calibrating bilirubin test card system and method

A sample of blood is placed on a bilirubin test strip and plasma separated from the red blood cells. The bilirubin test strip is located on a test card along with a set of calibration images, the colors of the calibration images being associated with known plasma bilirubin levels. A photograph is taken of the test card. The bilirubin level of the blood sample is determined by, within the photograph, interpolating the color of the plasma and the colors of the closest colored calibration images.

Device and system for analyzing a sample, particularly blood, as well as methods of using the same
11543408 · 2023-01-03 · ·

The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.

Safety light curtain to disable carousel rotation
11519925 · 2022-12-06 · ·

A digital slide scanning apparatus includes a safety light curtain that operates to disable the motor that rotates the carousel when the presence of an object (e.g., the fingers of an operator) is detected within a predetermined area of the carousel. The light curtain also operates to disable the motor that rotates the carousel when an improperly positioned glass slide or slide rack is detected. The digital slide scanning apparatus also includes a multi-color status indicator for each rack slot that indicates the rack slot location of an improperly positioned glass slide or slide rack.

Chemical liquid dispensing apparatus and chemical liquid discharging device

A liquid discharging device to be used with a liquid dispensing apparatus includes a discharging portion configured to discharge a liquid based on a control signal from the liquid dispensing apparatus on which the liquid discharging device is mounted, and a sheet material having a characteristic configured to be changed by the liquid dispensing apparatus after a discharge of the liquid by the discharging portion.

Test strip and method for manufacturating test strips
11583850 · 2023-02-21 · ·

The application discloses a test strip and a method for manufacturing the test strip. The test strip comprises a base layer; an intermediate layer overlaid on the base layer; a blood retaining layer comprising a slit and a blood retaining region fluidly commuted with the slit and overlaid on the intermediate layer; an upper layer overlaid on the blood retaining layer; a reagent disposed on a surface of the intermediate layer and exposed to the slit, wherein there are an expectedly predetermined depth and a measured depth from an interface between the slit and the upper layer to an upper surface of the intermediate layer; and a classification mark representing a compensation factor and disposed on an upper surface of the upper layer or a lower surface of the base layer; wherein the compensation factor is the product of a difference between the predetermined depth and the measured depth and a reciprocal of the predetermined depth.

Device and system for analyzing a sample, particularly blood, as well as methods of using the same
20230078489 · 2023-03-16 · ·

The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g., 0.5 μL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.

Methods and Systems for Improved Quality Assurance for High-Throughput Analysis
20220326266 · 2022-10-13 ·

Disclosed are methods and systems for confirming the identification of samples processed by a high-throughput analytical technique. The method may include the steps of distributing a plurality of individual samples to individual predetermined positions of a multi-sample test unit and distributing an identifier material to at least one predetermined position of the multi-sample test unit. The method may also include determining the absence or presence of an analyte in the plurality of individual samples, and determining the absence or presence of the identifier material, wherein the presence of the identifier material at the predetermined position of the multi-sample test unit is used to confirm the identity of the plurality of individual samples positioned in the multi-sample test unit. Also disclosed are systems for performing the disclosed methods or any of the steps of the disclosed methods. The methods and systems may be applied to high-throughput LC-MS/MS or other analytical methods.

SYSTEM AND METHOD FOR MELTING CURVE NORMALIZATION

The present invention relates to methods for the analysis of nucleic acids present in biological samples, and more specifically to normalize a high resolution melt curve to assist in the identification of one or more properties of the nucleic acids. The present invention provides methods and systems that incorporate a background identification algorithm according to invention principles using raw melt curve data to identify reactions that are unrelated actual DNA melt reactions. Furthermore, a web-based application for analyzing experimental data is provided. The raw experimental data obtained from a variety of instruments is processed and analyzed on a server and presented to a user through a user interface (UI).

VIEWER DEVICE AND METHODS FOR MAKING THE SAME
20170361324 · 2017-12-21 ·

A viewer device for observing and recording images of materials, such as chemical and biological materials is described. The viewer device includes a housing that provides a chamber for receiving a sample or a sample container that contains a sample of a material (e.g., chemical or biological material). The housing includes a viewing window for observing the sample, a port through which the sample or the sample container can be introduced to or removed from the chamber, and a coupling mechanism configured to removably and replaceably couple the housing to an observational device, such as a camera equipped device.