Reagent devices including a liquid container and a reagent insert are provided. Aspects of the reagent insert include a first dried reagent composition and a second dried reagent composition distinctly positioned on one or more surfaces of a solid support. Also provided are methods of making and using the reagent device or reagent insert, as well as systems and kits including the same.

The present disclosure relates to a biological test cassette and a medical test system, the biological test cassette comprising a support, a cassette body, a chip, a first connecting tube and a second connecting tube. The support is provided with a first via hole. The cassette body is provided with a second via hole corresponding to the position of the first via hole, mounted on a top surface of the support, and further provided with a pretreatment chamber and a first flow channel in communication with the pretreatment chamber. The chip is slidably provided on a bottom surface of the support, and provided with an analyzing and processing chamber and a second flow channel in communication with the analyzing and processing chamber. The second connecting tube can be freely bent and deformed during the process of pulling the chip out from or pushing the chip back into the support.

A microfluidic device for analyzing permeability of substances through a membrane. Flow channels pass respective fluid flows with the substances through the housing between respective connectors. An access cavity extends from outside into the housing through the first flow channel and into the second flow channel for accessing an inside of the housing. The membrane can be placed over a cavity opening forming a fluid interconnection between overlapping areas of the flow channels A clamping ring in the first flow channel holds the sample membrane in place over the cavity opening while the membrane is exposed to the respective fluid flows through the flow channels on either sides of the membrane.

A nucleic acid extraction system, comprising: a nucleic acid extraction plate, and a pipetting device and positive pressure device that are arranged side by side, the pipetting device comprising: an infusion device, an infusion device mounting frame, an infusion device driving unit, and a plurality of infusion units, each of the infusion units comprising: a reagent supply device and a reagent flow controller; the positive pressure device comprises: a plug, an air pipe, a positive pressure provider and a positive pressure driving device. The nucleic acid extraction system is highly efficiency and low-cost when extracting nucleic acid.

A diffusion/permeation cell, commonly referred to as a Franz cell, is provided for topical or transdermal drug delivery research and development in the pharmaceutical industry. The cell comprises a receptor container, a donor chamber, a quick clamping apparatus, and/or an assembly tool. Systems and methods provide a cost-effective diffusion cell, especially for use with an automatic diffusion release testing system.

A storage assembly for two substances to be mixed prior to use, includes a closable dropper tip (3). A first storage chamber (7) is formed by the closable dropper tip (3) and a first container part (2, 4), the first container part (2, 4) being provided with at least one aperture (43). A second storage chamber (8) is formed by a second container part (5) which includes an open end part (52, 53) that closes off the at least one aperture (43) in a first operational position. The first and second container parts (2, 4; 5, 6) are moveable with respect to each other, and are in fluid communication through the at least one aperture (43) in a second operational position wherein the total flow surface area of the at least one aperture (43) is at least equal to a cross sectional area of the first container part.

Freshly obtained blood samples are deposited into a device that contains blood sample carriers, each of the carriers is designed to hold a fixed amount of blood and allow excess blood sample to flow through and be discarded. A desiccant within the blood sample carrier aids with the drying of the blood and the discarding of the excess sample blood. The device is stored/transported within a modified atmosphere package comprised of an impermeable sealable bag and an oxygen scavenger compound for removing oxygen from the bag.

A method and an automated liquid handling system for the isolation of particles from a biological sample are provided. A column, a container and a filtration unit which are adapted to be used in such a method and system are provided. The column can include a section comprising a plurality of microbeads retained there.

A medical apparatus and method of preparing one or more cell blocks. The medical apparatus comprises at least one elongate tubular body having a proximal end and a distal end and filter assembly comprising a filter membrane and a border configured to engage the tubular body. The filter membrane and the border are each formed from material that is sectionable.

A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.