The present invention relates to devices and methods for collecting liquid samples such as for removing a target liquid sample fraction from a larger liquid sample, e.g., from a biological sample. These devices and methods are particularly useful for rapidly and cost-effectively removing the buffy coat layer from an anticoagulated blood sample. These devices and methods have the advantage that the removal can be made on blood sample processed by ordinary centrifugation and do not require more complicated or costly processing techniques such as density gradient centrifugation.

This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

A test cartridge for evaluating biological fluids can have a sensor flow cell defining a flow path for selectively passing a test fluid or biological fluid across a sensor to evaluate the sensor or the biological fluid. The test cartridge can include a sample port and at least one deformable reservoir, both formed as part of the test cartridge and fluidly connected to the flow path upstream of the sensor. A biological fluid can be manually fed into the flow path through the sample port for evaluation by the sensor. Before the biological fluid is fed through the sample port, the deformable reservoir can be manually ruptured to pass the test fluid contained within the reservoir across the sensor to first evaluate the sensor. In an example, the deformable reservoir can include a first reservoir containing a liquid quality control (LQC) fluid and a second reservoir containing a calibration fluid.

Provided are a fluorescence generating device and a digital PCR analysis system including the same. The fluorescence generating device includes a clad layer on a substrate, an optical waveguide arranged in a first direction within the clad layer, and a housing which is disposed on the optical waveguide and the clad layer and has a micro fluid channel extending in a second direction. The optical waveguide includes an input waveguide which is provided within one side of the clad layer and provides excitation light to a liquid drop within the micro fluid channel to generate fluorescent light, and an output waveguide which is provided within the other side of the clad layer and has an output inclined surface that reflects the fluorescent light.

This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

A fabric based microfluidic point of care at home diagnostic system is disclosed. The system comprising a fabric substrate one or more hydrophobic threads bound with one r more hydrophilic threads by means of weaving, knitting, embroidering, or sewing. The fabric is configured to define a flow path for a sample to flow from an introduction zone, to a preparation zone, to a testing zone, in a pattern sufficient to optimize the sample analysis required for sample diagnostic tests. The system further comprises one or more mechanical stages and one or more fluid cartridges. The mechanical stages comprise electrical and/or analytical equipment configured to record, detect, analytes or facilitate chemical reactions and/or condition of the air above the fabric to ensure sufficient for analysis. The fluid cartridges are attached to the edge of the fabric in certain zones to supply the fabric with reagents required for analysis in that zone.

The present invention provides methods, devices, and kits to improve procedures for reducing carbohydrates, such as glycans released from glycoconjugates, or for labeling carbohydrates by reductive amination.

There is provided a biomolecule collection device, comprising: a fluid chamber having a plurality of inner walls; and a plurality of nanowires disposed on two or more inner walls of the plurality of inner walls of the fluid chamber.

A manufacturing method of a sample collector for collection and transport of biological liquid samples, which includes a supporter, and a collecting part which is formed at an end portion of the supporter and to which fiber yarns are planted, includes the steps of: A) preparing two or more fiber yarns which are different from each other in at least one of length and width; and B) planting each of the fiber yarns to the collecting part based on a flocking method, wherein the step B) comprises the steps of: B1) mixing and putting the fiber yarns into a planting container so that the fiber yarns are distributed evenly; B2) inserting the collecting part into the planting container and applying adhesive onto the surface of the collecting part; and B3) planting the fiber yarns to the collecting part by electrostatic charge of each of the fiber yarns.