Systems and methods are provided for processing seeds collected from a field. One example system includes a trailer supporting a hopper configured to hold seeds to be devitalized, a mill configured to devitalize the seeds held in the hopper, and a spreader configured to discharge the devitalized seeds from the system. A first transport assembly interconnects the hopper and the mill, on the trailer, to transport the seeds from the hopper to the mill. And, a second transport assembly interconnects the mill and the spreader, on the trailer, to transport the devitalized seeds from the mill to the spreader.

Systems and methods are provided for processing seeds collected from a field. One example system includes a trailer supporting a hopper configured to hold seeds to be devitalized, a mill configured to devitalize the seeds held in the hopper, and a spreader configured to discharge the devitalized seeds from the system. A first transport assembly interconnects the hopper and the mill, on the trailer, to transport the seeds from the hopper to the mill. And, a second transport assembly interconnects the mill and the spreader, on the trailer, to transport the devitalized seeds from the mill to the spreader.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

A device for comminuting bulk material grains (K) having a first element, designed as a rotor having a cylindrical circumferential surface with a first surface (31) and a first receiving portion (41), and a second element designed as a shear strip (51) having a second surface (61) and a second receiving portion (71), and a supply unit. The first and the second surfaces (31, 61) lie parallel to and face one another. The first and second elements are relatively movable between first and second positions (P1, P2) in a plane of the first and the second surfaces (31, 61). In the first position (P1), the first and second receiving portion (41, 71) communicate with one another, via a passage (9) forming a receptacle, in which the bulk material grain (K) can be positioned, and, upon moving to the second position (P2), a cross section of the passage (9) is narrowed.

A device for comminuting bulk material grains (K) having a first element, designed as a rotor having a cylindrical circumferential surface with a first surface (31) and a first receiving portion (41), and a second element designed as a shear strip (51) having a second surface (61) and a second receiving portion (71), and a supply unit. The first and the second surfaces (31, 61) lie parallel to and face one another. The first and second elements are relatively movable between first and second positions (P1, P2) in a plane of the first and the second surfaces (31, 61). In the first position (P1), the first and second receiving portion (41, 71) communicate with one another, via a passage (9) forming a receptacle, in which the bulk material grain (K) can be positioned, and, upon moving to the second position (P2), a cross section of the passage (9) is narrowed.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.