Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

In at least one illustrative embodiment, an electromagnetic filter may include a transfer pipe and multiple electromagnetic filter elements positioned in an interior volume of the pipe. Each electromagnetic filter element includes a support comb, a solenoid coupled to the support comb, and multiple magnetic members arranged in a planar array positioned within an opening of the support comb. Each magnetic member may rotate about an end that is coupled to the support comb. The magnetic members may be magnetostrictive sensors and may include a biorecognition element to bind with a target microorganism. A method for fluid filtration includes coupling the electromagnetic filter between a fluid source and a fluid destination, energizing the solenoids of each electromagnetic filter elements, and flowing a fluid media through the transfer pipe of the electromagnetic filter. The fluid media may be liquid food such as fruit juice. Other embodiments are described and claimed.

In at least one illustrative embodiment, an electromagnetic filter may include a transfer pipe and multiple electromagnetic filter elements positioned in an interior volume of the pipe. Each electromagnetic filter element includes a support comb, a solenoid coupled to the support comb, and multiple magnetic members arranged in a planar array positioned within an opening of the support comb. Each magnetic member may rotate about an end that is coupled to the support comb. The magnetic members may be magnetostrictive sensors and may include a biorecognition element to bind with a target microorganism. A method for fluid filtration includes coupling the electromagnetic filter between a fluid source and a fluid destination, energizing the solenoids of each electromagnetic filter elements, and flowing a fluid media through the transfer pipe of the electromagnetic filter. The fluid media may be liquid food such as fruit juice. Other embodiments are described and claimed.

A magnetic rod guide for a filter comprises a base for attachment to part of a filter, a through aperture through which a magnetic rod can move, and resilient engagement means including at least one resilient latch for holding the magnetic rod in one or more fixed positions relative to the guide, the or each resilient latch further being adapted to allow movement of a magnetic rod through the through aperture in either direction, for insertion into the filter or withdrawal from the filter into one of the fixed positions.

A magnetic rod guide for a filter comprises a base for attachment to part of a filter, a through aperture through which a magnetic rod can move, and resilient engagement means including at least one resilient latch for holding the magnetic rod in one or more fixed positions relative to the guide, the or each resilient latch further being adapted to allow movement of a magnetic rod through the through aperture in either direction, for insertion into the filter or withdrawal from the filter into one of the fixed positions.

A magnetic matrix for magnetic separation of particles in a material feed includes a plurality of grooved plates having first and second sides that both have an alternating series of teeth and grooves therealong, each grooved plate having an offset alignment in which teeth and grooves on a first side of a plate are laterally offset from teeth and grooves on a second side of the same plate. Also provided are methods of using magnetic matrices to separate magnetic ores, with the methods characterized by a negative correlation in which magnetic matrices constructed with grooved plates having larger pitches are used for the separation of ultrafine particles.

A magnetic matrix for magnetic separation of particles in a material feed includes a plurality of grooved plates having first and second sides that both have an alternating series of teeth and grooves therealong, each grooved plate having an offset alignment in which teeth and grooves on a first side of a plate are laterally offset from teeth and grooves on a second side of the same plate. Also provided are methods of using magnetic matrices to separate magnetic ores, with the methods characterized by a negative correlation in which magnetic matrices constructed with grooved plates having larger pitches are used for the separation of ultrafine particles.

The present invention relates to a method for separating biomolecules from a liquid medium. The method comprises adding magnetic nanoparticles to the liquid medium comprising the biomolecules, the biomolecules each adapted to bind to respective surfaces of the magnetic nanoparticles; bringing the liquid medium to which the magnetic nanoparticles have been added into contact with a collector; applying a magnetic field to the liquid medium in contact with the collector to attract the magnetic nanoparticles ound with the biomolecules to a surface of the collector; and applying an electric potential to the surface of the collector to release the biomolecules from the magnetic nanoparticles.

A method for filtering magnetic particles includes spinning a filter including a plurality of pores within a substrate. The method further includes applying, subsequent to spinning the filter, an external magnetic field to the filter. The method includes disposing a solution including a first particle and a second particle onto the filter. The first particle includes a magnetic particle of interest. The method further includes separating the first particle from the second particle by capturing the first particle within a pore of the plurality of pores within the substrate.