Patent classifications
B03C1/32
Magnet and device for magnetic density separation
A planar magnet for magnetic density separation, comprising an array of pole pieces succeeding in longitudinal direction of a mounting plane, each pole piece having a body extending transversely along the mounting plane with a substantially constant cross section that includes a top segment that is curved to distribute the magnetic field associated with the top surface of the pole piece such that its strength transverse to the mounting plane is substantially uniformly distributed in planes parallel to the mounting plane, the curved top segments having a width (w) in longitudinal direction of the mounting plane and a maximum height (h) transverse to the mounting plane, wherein the top segments of successive pole pieces are unequal in height and/or width.
Magnet and device for magnetic density separation
A planar magnet for magnetic density separation, comprising an array of pole pieces succeeding in longitudinal direction of a mounting plane, each pole piece having a body extending transversely along the mounting plane with a substantially constant cross section that includes a top segment that is curved to distribute the magnetic field associated with the top surface of the pole piece such that its strength transverse to the mounting plane is substantially uniformly distributed in planes parallel to the mounting plane, the curved top segments having a width (w) in longitudinal direction of the mounting plane and a maximum height (h) transverse to the mounting plane, wherein the top segments of successive pole pieces are unequal in height and/or width.
SYSTEMS AND METHODS FOR BEAD-BASED ASSAYS IN FERROFLUIDS
Some embodiments of the present disclosure are directed to systems and methods for separating, directing, and/or extracting a target molecule from a mix of molecules and may comprise a plurality of non-magnetic beads suspended in a ferro fluid, where the non-magnetic beads may be functionalized with at least one predetermined first molecule configured to bind with a target particle. A microfluidic device may be included which may comprise at least one microfluidic channel, the device configured to dynamically and/or statically receive an amount of the mix. Magnetic field means may be included and may be configured to apply a magnetic field to at least a portion of the at least one channel to exert an indirect force on the non-magnetic heads in the ferro fluid mix, and separate the non-magnetic beads from the ferrofluid. The beads may then be directed to at least one receptor region. At least one outlet may be provided which is arranged to be in communication with the at least one microfluidic channel, the at least one outlet may be configured to receive and extract the separated non-magnetic beads from the ferrofluid.
Label-free cellular manipulation and sorting via biocompatible ferrofluids
A device for separating a sample of cells suspended in a bio-compatible ferrofluid is described, The device includes a microfluidic channel having a sample inlet, at least one outlet and a length between the same inlet and the at least one outlet, wherein a sample can be added to the sample inlet and flow along the microfluidic channel length to the at least one outlet. The device includes a plurality of electrodes and a power source for applying a current to the plurality of electrodes to create a magnetic field pattern along the microfluidic channel length. The present invention also includes a method of using said device for separating at least one cell type.
Label-free cellular manipulation and sorting via biocompatible ferrofluids
A device for separating a sample of cells suspended in a bio-compatible ferrofluid is described, The device includes a microfluidic channel having a sample inlet, at least one outlet and a length between the same inlet and the at least one outlet, wherein a sample can be added to the sample inlet and flow along the microfluidic channel length to the at least one outlet. The device includes a plurality of electrodes and a power source for applying a current to the plurality of electrodes to create a magnetic field pattern along the microfluidic channel length. The present invention also includes a method of using said device for separating at least one cell type.
Systems and methods for bead-based assays in ferrofluids
Some embodiments of the present disclosure are directed to systems and methods for separating, directing, and/or extracting a target molecule from a mix of molecules and may comprise a plurality of non-magnetic beads suspended in a ferro fluid, where the non-magnetic beads may be functionalized with at least one predetermined first molecule configured to bind with a target particle. A microfluidic device may be included which may comprise at least one microfluidic channel, the device configured to dynamically and/or statically receive an amount of the mix. Magnetic field means may be included and may be configured to apply a magnetic field to at least a portion of the at least one channel to exert an indirect force on the non-magnetic heads in the ferro fluid mix, and separate the non-magnetic beads from the ferrofluid. The beads may then be directed to at least one receptor region. At least one outlet may be provided which is arranged to be in communication with the at least one microfluidic channel, the at least one outlet may be configured to receive and extract the separated non-magnetic beads from the ferrofluid.
Systems and methods for bead-based assays in ferrofluids
Some embodiments of the present disclosure are directed to systems and methods for separating, directing, and/or extracting a target molecule from a mix of molecules and may comprise a plurality of non-magnetic beads suspended in a ferro fluid, where the non-magnetic beads may be functionalized with at least one predetermined first molecule configured to bind with a target particle. A microfluidic device may be included which may comprise at least one microfluidic channel, the device configured to dynamically and/or statically receive an amount of the mix. Magnetic field means may be included and may be configured to apply a magnetic field to at least a portion of the at least one channel to exert an indirect force on the non-magnetic heads in the ferro fluid mix, and separate the non-magnetic beads from the ferrofluid. The beads may then be directed to at least one receptor region. At least one outlet may be provided which is arranged to be in communication with the at least one microfluidic channel, the at least one outlet may be configured to receive and extract the separated non-magnetic beads from the ferrofluid.
MAGNETIC SEPARATION OF ELECTROCHEMICAL CELL MATERIALS
A process. The process includes forming a slurry comprising electrode active material particles of one or more lithium-ion electrochemical cells, magnetizing the electrode active material particles and separating the magnetized electrode active material particles from the slurry.
MAGNETIC SEPARATION OF ELECTROCHEMICAL CELL MATERIALS
A process. The process includes forming a slurry comprising electrode active material particles of one or more lithium-ion electrochemical cells, magnetizing the electrode active material particles and separating the magnetized electrode active material particles from the slurry.
SYSTEM AND METHOD FOR CELL LEVITATION AND MONITORING
Magnetic cell levitation and cell monitoring systems and methods are disclosed. A method for separating a heterogeneous population of cells is performed by placing a microcapillary channel containing the heterogeneous population of cells in a magnetically-responsive medium in the disclosed levitation system and separating the cells by balancing magnetic and corrected gravitational forces on the individual cells. A levitation system is also disclosed, having a microscope on which the microcapillary channel is placed and a set of two magnets between which the microcapillary channel is placed. Additionally, a method for monitoring cellular processes in real-time using the levitation system is disclosed.