B04B5/0407

AUTOMATED SYSTEM FOR PROCESSING PARTICLES

A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.

Cell washing device and method

A cell washer is disclosed. The cell washer includes a vessel configured to hold cells. The vessel includes an elongated body including an opening, an inner surface, and a pocket defined by a first inner surface portion of the inner surface disposed between and radially outward relative to a second inner surface portion and a third inner surface portion of the inner surface, and a cavity. The vessel also includes an actuating device capable of causing the vessel to spin about an axis.

Biological material, measuring instrument
11536635 · 2022-12-27 · ·

A biological material measuring instrument is described. The biological material measuring instrument includes a rotating body and a main body. The rotating body includes one or more cartridge holders having cuvettes in which a reagent and an analyte in a sample react. The main body includes a pair of light-emitting parts and light-receiving parts to optically measure the analyte in the sample. The rotating body further includes a light-emitting optical waveguide for guiding the light of the light-emitting parts to the cuvette and a light-receiving optical waveguide for guiding.

Centrifugal separation container and centrifugal separator
11534773 · 2022-12-27 · ·

A centrifugal separation container which is revolved around a rotation axis, includes: a separation part which includes a distal region which is disposed on a distal side than a liquid-to-be-treated supply port and a proximal region which is disposed on a proximal side than the liquid-to-be-treated supply port, with respect to the rotation axis, and in which a liquid-to-be-treated discharge port is provided in the proximal region; and a recovery part which is disposed on a distal side than the distal region with respect to the rotation axis, communicates with a distal end portion of the distal region through a communication path, and is filled with a recovery liquid for dispersing dispersoids that are to be centrifuged in a liquid to be treated.

BATCH BIOPROCESSING CENTRIFUGE ROTOR
20230086155 · 2023-03-23 ·

A rotor for use in a centrifuge, and adapters for coupling one or more processing containers to the rotor. The rotor includes a rotor body having a plurality of receptacles each configured to receive an adapter. Each adapter includes an outer surface configured to interface with one of the receptacles, and one or more cavities each configured to accept a processing container. The rotor may also include a rotor liner positioned between the adapters and the rotor body. The rotor liner engages the receptacles of the rotor body, and provides a plurality of receptacles that receive the adapters, thereby providing an interface between the adapters and the receptacles of the rotor body.

Centrifuge and method for cleaning a centrifuge
20230077651 · 2023-03-16 ·

The invention relates to a centrifuge for cleaning a reaction vessel unit and to a method for cleaning such a centrifuge. The centrifuge has a rotor and a rotor chamber, in which the rotor is arranged and mounted, the rotor features a receiving area for receiving the reaction vessel unit. The rotor chamber is limited by a housing, the housing having an outlet to drain the liquid discharged from the reaction vessels and being provided with an inlet for filling the rotor chamber with a cleaning solution in such a way, when the rotor rotates, the rotor 2 is at least partially immersed in the cleaning solution and distributes it in rotor chamber and/or the inlet is designed in such a way that the cleaning solution is distributed in rotor chamber when it is supplied by the rotating rotor.

Disposable Centrifuge Pot
20220331818 · 2022-10-20 · ·

A pot for centrifugal separation of a biological fluid into multiple components. The pot comprises a wall (111) around a central axis (112), a top end (121) and a bottom end (113). The pot also comprises a plurality of baffles (114) protruding from the wall (111) into an inner volume of the pot, and/or a protrusion from the bottom end into the inner volume and around the central axis. Also, a consumable cartridge comprising the pot, a cartridge body adapted to receive the pot, and a first holding means. The first holding means is for holding the pot at least partly within the cartridge body, and is adapted to allow the pot to rotate.

BIOLOGICAL MATERIAL MEASURING INSTRUMENT
20230132344 · 2023-04-27 · ·

A biological material measuring instrument is described. The biological material measuring instrument includes a rotating body and a main body. The rotating body includes one or more cartridge holders having cuvettes in which a reagent and an analyte in a sample react. The main body includes a pair of light-emitting parts and light-receiving parts to optically measure the analyte in the sample. The rotating body further includes a light-emitting optical waveguide for guiding the light of the light-emitting parts to the cuvette, and a light-receiving optical waveguide for guiding.

Automated sample processing, fluid distribution, and sedimentation assay

The disclosure describes methods and devices with which to process and analyze difficult chemical, biological, environmental samples including but not limited to those containing bulk solids or particulates. The disclosure includes a cartridge which contains a separation tube as well as one or more valves and cavities for receiving raw sample materials and for directing and containing various fluids or samples. The cartridge may contain a separation fluid or density medium of defined density, and structures which direct particulates toward defined regions of the cartridge. Embodiments can include a rotational device for rotating the cartridge at defined rotational rates for defined time intervals. Embodiments allowing multiple assays from a single sample are also disclosed. In some embodiments, this device is used for direct processing and chemical analysis of food, soil, blood, stool, motor oil, semen, and other samples of interest.

CELL WASHING DEVICE AND METHOD
20230119931 · 2023-04-20 ·

A cell washer is disclosed. The cell washer includes a vessel configured to hold cells. The vessel includes an elongated body including an opening, an inner surface, and a pocket defined by a first inner surface portion of the inner surface disposed between and radially outward relative to a second inner surface portion and a third inner surface portion of the inner surface, and a cavity. The vessel also includes an actuating device capable of causing the vessel to spin about an axis.