An object of the present invention is to provide a safety cabinet that allows a clearer observation of contamination of an operation stage surface. In order to realize the object, the safety cabinet is configured to include an operation space including an operation stage; a front panel formed in a front surface of the operation space; an operation opening provided in a lower portion of the front panel; a suction port that is provided in the vicinity of the operation opening on a front side of the operation stage to lead downward; and an air circulation path through which air suctioned from the suction port flows along a lower portion, a back surface, and an upper portion of the operation space, in which the operation stage is made of a transparent material, and a light source is provided to irradiate the operation stage with a light from a side of the operation stage, which is opposite to the operation space.

The subject matter is the assembly of a containment means with an aseptic working chamber and associated decontamination arrangement. The working chamber is delimited at the bottom by a base, and above the working chamber is a circulating air zone, in which a circulating air filter with a circulating air fan is arranged. The circulating air zone and the working chamber are delimited towards the outside by a housing. At least a first returning air channel leads from the working chamber into the circulating air zone. A returning air filter is fluidically connected to the returning air channel, specifically is arranged facing the circulating air zone. The returning air filter can be arranged at the opening of the returning air channel into the circulating air zone or arranged in the circulating air channel, set back from the opening. The returning air filter and the circulating air filter are in the form of a plate filter or an exchangeable filter cartridge or a replaceable filter insert. A single returning air filter or a series of interacting returning air filters and a single circulating air filter or a series of interacting circulating air filters can be installed. Containment means in which larger volumes of air are to be processed also have a second returning air channel at or in which a returning air filter is also installed.

A fume cupboard, of the type comprising a framework with two front uprights (2a,2b), two rear uprights (3a,3b), a rear panel (11), two side panels (6,7), an upper panel (8) and a sash (4) consisting of a frame (12) and at least one panel (13) for closing an inner chamber (1 0) of said fume cupboard (1). The fume cupboard of the invention comprises a transmission system (14) for transmission of the vertical movements of said sash (4) located inside the abovementioned front uprights (2a,2b), or inside said front uprights (2a,2b) and said rear uprights (3a,3b).

A method is provided for detecting primary gas flows (18) in flow chambers (10). The primary gas (18) flowing in a flow chamber (10) is locally seeded with a seed substance and the movement of the seed substance, representative of the flow of the primary gas (18), is detected by imaging by an image detector (28) and an imaging optics (30) arranged in front of said image detector (28). A gas mixture (34) that moves along with the primary gas (18) without relative motion and that has a refractive index distinguishable from that of the primary gas (18) is used as the seed substance, and imaging detection is carried out by a background schlieren measurement method.

A biofabrication system includes a workstation and an articulating arm disposed within a work area of a biosafety cabinet. The workstation includes a stage for biofabrication. The biosafety cabinet includes an integration port that provides access to the work area through a wall of the biosafety cabinet. The articulating arm may be positioned to reach the workstation and the integration port.

A containment system and assembly for the automated production of pharmaceutical or biotechnical articles is provided. The containment system has a housing within which there is an inner chamber having at least one through opening. One or more robots are installed in the chamber, which have a manipulating element on the pivotable arms, which can move within a pivot range. One or more process units are installed in the chamber for the production of the articles. The chamber includes a process space for the production of the articles and a tub-shaped base space for anchoring the feet of the robots to the side surfaces inside the base space. The manipulating element functions as a gripping and transportation device for inspecting the articles or article parts and/or for the production of the articles.

A solvent containment and solvent handling process interlocking system is described that can be used as a ventilation and spill management system for the storage and use of hazardous and volatile chemicals and solvents in an ordinary or non-hazardous location. The vented solvent containment system has a containment tray for secondary solvent containment and air regulatory to supply negative air pressure to draw in any evaporated solvent from the containment tray to a safe exhaust location. A safety sensor in the solvent containment system is interlocked with the solvent handling and solvent control system to slow or stop solvent flow in the event of a potentially hazardous solvent leak.

A method for the preparation of pharmaceutical products is provided that utilizes a machine having a containing liner, a dosing chamber for preparing at least one pharmaceutical product accommodated within the containing liner, and a pneumatic ventilation device for feeding two air flows through the dosing chamber and through the containing liner, respectively. Operation of the pneumatic ventilation device is selectively controlled so that the containing liner has inside a pressure lower than a pressure existing within the dosing chamber and than a pressure existing in the environment outside the containing liner itself.

An apparatus including a sensor configured to sense total pressure within an inner chamber of a housing, and to sense differential pressure between the inner chamber of the housing and work area outside of the housing; a computer processor configured to receive signals from the sensor based on the total pressure and the differential pressure; and wherein the computer processor controls the rate at which the flapper oscillates based on the total pressure signal from the sensor, to thereby control the direction of flow of air from the inner chamber of the housing through the plurality of openings of the blade, through the plurality of openings of the teeth, for optimum containment with ultra stable vortex inside the chamber ; and controls the rate at which exhaust damper modulates based on differential pressure signal to maintain constant face velocity at the apparatus user opening and out an exhaust opening of the housing.

A fume hood adapted to be connected to an exhaust system has a ventilated chamber having an access opening, and at least one horizontally sliding sash or panel at the access opening that is configured to cover and uncover portions of the access opening. Each horizontally sliding panel has a peripheral edge that convexly curves into the chamber towards a centerline of the at least one horizontally sliding panel. In some embodiments, the peripheral edge is convexly curved in an arc of between about ninety degrees and about one hundred eighty degrees (90°-180°). The exhaust system creates air flow into the chamber and the curved peripheral edge produces controlled air flow patterns into the chamber. The curved edge is aerodynamically designed to help shed vortices and prevent accumulation of concentrations on the inside edge of the each panel typical of conventional fume hood sashes/panels.