Barbed medical devices include a crown interconnecting a pair of legs and at least one barb extending from each of the legs. The at least one barb may define an inner surface with a first portion disposed at a first orientation relative to a longitudinal axis of the leg, a second portion disposed at a second orientation relative to the longitudinal axis, and optionally, a third portion disposed at a third orientation relative to the longitudinal axis of the leg.

Barbed medical devices include a crown interconnecting a pair of legs and at least one barb extending from each of the legs. The at least one barb may define an inner surface with a first portion disposed at a first orientation relative to a longitudinal axis of the leg, a second portion disposed at a second orientation relative to the longitudinal axis, and optionally, a third portion disposed at a third orientation relative to the longitudinal axis of the leg.

Embodiments described herein provide a fastening device such as a nail or staple having at least one projection each extending away from the body at an angle and away from a tip of the body. For example, in the case of a nail, there can be two or more projections extending from the elongated member of the nail each at a substantially equal distance from the head and/or along the length of the elongated member each spaced at substantially equal distances apart. In the case of a staple, there can be at least one projection connected to the interior surface of a first leg of the staple, that surface being substantially opposite to an interior surface of a second leg of the staple. The tip can be sharp or not sharp. The projections can be connected to exterior surfaces of the staple's legs.

A method of forming a surgical staple comprising a base, a first staple leg, and a second staple leg is disclosed. The method comprises positioning the first staple leg within a first cup of a staple pocket and positioning the second staple leg within a second cup of the staple pocket, contacting the first staple leg to bend the first staple leg toward a first side of the base wherein the first staple leg is maintained in an unformed and unheated configuration until a first compressive force is applied to the first staple leg, and contacting the second staple leg to bend the second staple leg toward a second side of the base wherein the second staple leg is maintained in an unformed and unheated configuration until a second compressive force is applied to the second staple leg.