An article manufactured in a mould and which comprises a structural composite of plastics layers, the article having a wall defining an internal space for holding contents therein; wherein, the wall is formed from at least two layers of plastics materials; wherein a first of said layers comprises a thermoplastics material and at least a second layer comprises a thermosetting resin and a fibrous layer.

A screw smelting machine melts raw materials with a different chemical ratio in a mixing funnel in a feeding order to prevent the long-range diffusion of a melt, and controls outflow at a suitable speed. A centrifugal casting machine solidifies the melt with the ingredients gradient varying into a radial ingredient gradient material by a centrifugal casting style. A temperature sensor monitors temperature of an outer surface of a centrifuge cavity of the centrifugal casting machine during centrifugal casting, and transmits the temperature to a control platform. The control platform determines an optimal flow rate of the melt at an end of screw rod according to ingredient gradient of ingredient radial-gradient pipe materials and a thickness of each component gradient material required with preparation, in combination with a real-time data fed back from the temperature sensor, and feeds back to a feeding end.

A screw smelting machine melts raw materials with a different chemical ratio in a mixing funnel in a feeding order to prevent the long-range diffusion of a melt, and controls outflow at a suitable speed. A centrifugal casting machine solidifies the melt with the ingredients gradient varying into a radial ingredient gradient material by a centrifugal casting style. A temperature sensor monitors temperature of an outer surface of a centrifuge cavity of the centrifugal casting machine during centrifugal casting, and transmits the temperature to a control platform. The control platform determines an optimal flow rate of the melt at an end of screw rod according to ingredient gradient of ingredient radial-gradient pipe materials and a thickness of each component gradient material required with preparation, in combination with a real-time data fed back from the temperature sensor, and feeds back to a feeding end.

Disclosed herein is a microneedle array comprising a substrate and a plurality of microneedles extending therefrom, wherein the microneedles comprise a biodegradable polymer and an effective amount of an analgesic or an anti-inflammatory therapeutic agent. Methods of using and making the microneedle array are also disclosed.

An article manufactured in a mould and which comprises a structural composite of plastics layers, the article having a wall defining an internal space for holding contents therein; wherein, the wall is formed from at least two layers of plastics materials; wherein a first of said layers comprises a thermoplastics material and at least a second layer comprises a thermosetting resin and a fibrous layer.

An article manufactured in a mould and which comprises a structural composite of plastics layers, the article having a wall defining an internal space for holding contents therein; wherein, the wall is formed from at least two layers of plastics materials; wherein a first of said layers comprises a thermoplastics material and at least a second layer comprises a thermosetting resin and a fibrous layer.

The invention relates to heat treatment of polymorphic semicrystalline or crystallizable polymers to increase the content of the highest melting crystalline form. Such heat treatment results in a polymer powder that has a consistent, uniform melting range, improved flow and improved durability of the powder particle size for applications that require powder flow at elevated temperatures. In addition to improved powder properties, the articles produced from the powders also exhibit better physical properties in both appearance and in mechanical properties. Thus the invention also includes polymer powders and articles produced by the described processes.

The invention relates to heat treatment of polymorphic semicrystalline or crystallizable polymers to increase the content of the highest melting crystalline form. Such heat treatment results in a polymer powder that has a consistent, uniform melting range, improved flow and improved durability of the powder particle size for applications that require powder flow at elevated temperatures. In addition to improved powder properties, the articles produced from the powders also exhibit better physical properties in both appearance and in mechanical properties. Thus the invention also includes polymer powders and articles produced by the described processes.

The invention relates to heat treatment of polymorphic semicrystalline or crystallizable polymers to increase the content of the highest melting crystalline form. Such heat treatment results in a polymer powder that has a consistent, uniform melting range, improved flow and improved durability of the powder particle size for applications that require powder flow at elevated temperatures. In addition to improved powder properties, the articles produced from the powders also exhibit better physical properties in both appearance and in mechanical properties. Thus the invention also includes polymer powders and articles produced by the described processes.

The invention relates to heat treatment of polymorphic semicrystalline or crystallizable polymers to increase the content of the highest melting crystalline form. Such heat treatment results in a polymer powder that has a consistent, uniform melting range, improved flow and improved durability of the powder particle size for applications that require powder flow at elevated temperatures. In addition to improved powder properties, the articles produced from the powders also exhibit better physical properties in both appearance and in mechanical properties. Thus the invention also includes polymer powders and articles produced by the described processes.