Methods are provided that involve the intentional and controlled precipitation of a drug or active agent, or a reduction of solubility of a polymer or other film-forming component of a formulation, or a combination of both methods, to improve the processes for making microneedles or other objects by casting into molds and the resulting parts produced by casting. The selective reduction in solubility of formulation components solves many problems associated with the casting of polymer formulations into molds. The methods are preferably adapted for making microneedles of biodegradable polymer and drug composites, and may also be used to produce other solid objects formed by casting into molds of compositions containing polymers and active agents.

A screw smelting machine melts raw materials with a different chemical ratio in a mixing funnel in a feeding order to prevent the long-range diffusion of a melt, and controls outflow at a suitable speed. A centrifugal casting machine solidifies the melt with the ingredients gradient varying into a radial ingredient gradient material by a centrifugal casting style. A temperature sensor monitors temperature of an outer surface of a centrifuge cavity of the centrifugal casting machine during centrifugal casting, and transmits the temperature to a control platform. The control platform determines an optimal flow rate of the melt at an end of screw rod according to ingredient gradient of ingredient radial-gradient pipe materials and a thickness of each component gradient material required with preparation, in combination with a real-time data fed back from the temperature sensor, and feeds back to a feeding end.

A screw smelting machine melts raw materials with a different chemical ratio in a mixing funnel in a feeding order to prevent the long-range diffusion of a melt, and controls outflow at a suitable speed. A centrifugal casting machine solidifies the melt with the ingredients gradient varying into a radial ingredient gradient material by a centrifugal casting style. A temperature sensor monitors temperature of an outer surface of a centrifuge cavity of the centrifugal casting machine during centrifugal casting, and transmits the temperature to a control platform. The control platform determines an optimal flow rate of the melt at an end of screw rod according to ingredient gradient of ingredient radial-gradient pipe materials and a thickness of each component gradient material required with preparation, in combination with a real-time data fed back from the temperature sensor, and feeds back to a feeding end.

The present disclosure relates to a casting device for producing a potting for a gas exchanger and a method for producing such a potting. Accordingly, a casting device is proposed for producing a potting for a gas exchanger under the influence of a centrifugal force, comprising a distributor comprising an opening and at least one continuous channel and adapted to receive a fluid potting material via the opening and to guide it via the at least one channel. The casting device further comprises a cassette defining an inner cavity for receiving gas exchanger elements and which is fluidly connected to the at least one channel. The distributor comprises at least two distributor components which, in the assembled state of the distributor, define the opening, are connected to one another in a leak-proof manner, and form the at least one channel between adjacent regions.

The present disclosure relates to a casting device for producing a potting for a gas exchanger and a method for producing such a potting. Accordingly, a casting device is proposed for producing a potting for a gas exchanger under the influence of a centrifugal force, comprising a distributor comprising an opening and at least one continuous channel and adapted to receive a fluid potting material via the opening and to guide it via the at least one channel. The casting device further comprises a cassette defining an inner cavity for receiving gas exchanger elements and which is fluidly connected to the at least one channel. The distributor comprises at least two distributor components which, in the assembled state of the distributor, define the opening, are connected to one another in a leak-proof manner, and form the at least one channel between adjacent regions.

In a method for fabricating a separation fence (1) to be used in a hydrometallurgical liquid-liquid solvent extraction settler, the fence is manufactured of polymer resin. The fence (1) is manufactured as a shell-like integral piece by rotational molding. The fence (1) is a rotationally molded shell-like integral piece.

In a method for fabricating a separation fence (1) to be used in a hydrometallurgical liquid-liquid solvent extraction settler, the fence is manufactured of polymer resin. The fence (1) is manufactured as a shell-like integral piece by rotational molding. The fence (1) is a rotationally molded shell-like integral piece.

A wheel for a vehicle is non-pneumatic (i.e., airless), may be designed to enhance its use and performance and/or use and performance of the vehicle, and may be manufactured efficiently, including by a single non-pneumatic tire molding operation that can allow rigid rim incorporation and complex tread implementation.

A wheel for a vehicle is non-pneumatic (i.e., airless), may be designed to enhance its use and performance and/or use and performance of the vehicle, and may be manufactured efficiently, including by a single non-pneumatic tire molding operation that can allow rigid rim incorporation and complex tread implementation.

An article manufactured in a mould and which comprises a structural composite of plastics layers, the article having a wall defining an internal space for holding contents therein; wherein, the wall is formed from at least two layers of plastics materials; wherein a first of said layers comprises a thermoplastics material and at least a second layer comprises a thermosetting resin and a fibrous layer.