Solid, non-melting polyurethanes having a glass transition temperature of at least 40° C. and free isocyanate groups are self-bonding materials that are useful in a variety of adhesive and molding operations. Under conditions of heat and moisture, these polyurethanes will self-bond. The polyurethanes can be used as adhesive coatings, which are solid and non-tacky and thus can be transported and stored easily under ambient conditions. These polyurethane adhesives are especially useful in applications in which, due to the location and/or orientation of the substrates, liquid or melting materials cannot be applied easily or will run off the substrates.

Solid, non-melting polyurethanes having a glass transition temperature of at least 40° C. and free isocyanate groups are self-bonding materials that are useful in a variety of adhesive and molding operations. Under conditions of heat and moisture, these polyurethanes will self-bond. The polyurethanes can be used as adhesive coatings, which are solid and non-tacky and thus can be transported and stored easily under ambient conditions. These polyurethane adhesives are especially useful in applications in which, due to the location and/or orientation of the substrates, liquid or melting materials cannot be applied easily or will run off the substrates.

In a method for the further processing of a product (30) that is preferably prefabricated in large numbers, the product has a surface (31) for an additive multi-dimensional application of material. Information for the additive multi-dimensional application of material is input into a device in which the multi-dimensional application of material is digitised from this information and is deconstructed into elements that are suitable for the additive application of the application of material to the surface (31). The prefabricated product (30) is introduced into a device (I) for additive application of the material application such that the elements for the additive multi-dimensional application of material on the surface (31) are assembled in accordance with the information using an additive manufacturing method. Because the surface is an individualising surface (31) of the prefabricated product, and because the additive application of material is a multi-dimensional individualisation that is intended and suitable for individualising the product, and because at least one of the prefabricated products is identified by the information and is provided individually with the multi-dimensional individualisation (32), a method is provided by which products that are prefabricated in relatively large numbers can be further processed, individualised or personalised to meet individual demands. The prefabricated product (30) is equipped with an associated information carrier for receiving the information for individualisation that supports the method sequence.

In a method for the further processing of a product (30) that is preferably prefabricated in large numbers, the product has a surface (31) for an additive multi-dimensional application of material. Information for the additive multi-dimensional application of material is input into a device in which the multi-dimensional application of material is digitised from this information and is deconstructed into elements that are suitable for the additive application of the application of material to the surface (31). The prefabricated product (30) is introduced into a device (I) for additive application of the material application such that the elements for the additive multi-dimensional application of material on the surface (31) are assembled in accordance with the information using an additive manufacturing method. Because the surface is an individualising surface (31) of the prefabricated product, and because the additive application of material is a multi-dimensional individualisation that is intended and suitable for individualising the product, and because at least one of the prefabricated products is identified by the information and is provided individually with the multi-dimensional individualisation (32), a method is provided by which products that are prefabricated in relatively large numbers can be further processed, individualised or personalised to meet individual demands. The prefabricated product (30) is equipped with an associated information carrier for receiving the information for individualisation that supports the method sequence.

A bioresorbable, implantable device having controlled drug delivery is disclosed herein. The bioresorbable, implantable device is configured as a film, a roll, a tube, and a stent. The bioresorbable, implantable device is configured to release an active ingredient (the “drug”) from the bioresorbable, implantable device when the bioresorbable, implantable device is implanted within a body. The bioresorbable, implantable device is configured to control the onset of the release of the drug, the sequence of drug delivery, and the duration of drug delivery by embedding the drug within at least one therapeutic layer positioned within bioresorbable, implantable device.

A bioresorbable, implantable device having controlled drug delivery is disclosed herein. The bioresorbable, implantable device is configured as a film, a roll, a tube, and a stent. The bioresorbable, implantable device is configured to release an active ingredient (the “drug”) from the bioresorbable, implantable device when the bioresorbable, implantable device is implanted within a body. The bioresorbable, implantable device is configured to control the onset of the release of the drug, the sequence of drug delivery, and the duration of drug delivery by embedding the drug within at least one therapeutic layer positioned within bioresorbable, implantable device.

A multilayer bioresorbable stent having sustained drug delivery is disclosed herein. The bioresorbable stent releases a therapeutic substance from the body of the bioresorbable stent starting when the bioresorbable stent is implanted within an anatomical lumen and ending when the entire mass of the bioresorbable stent is no longer present within the anatomical lumen. The bioresorbable stent releases the therapeutic substance gradually during the treatment as the mass of the each layer of the bioresorbable stent erodes. Methods of making the therapeutic layers within the bioresorbable sent are further disclosed. Sustained drug delivery reduces the risk of late and very late stent thrombosis.

A multilayer bioresorbable stent having sustained drug delivery is disclosed herein. The bioresorbable stent releases a therapeutic substance from the body of the bioresorbable stent starting when the bioresorbable stent is implanted within an anatomical lumen and ending when the entire mass of the bioresorbable stent is no longer present within the anatomical lumen. The bioresorbable stent releases the therapeutic substance gradually during the treatment as the mass of the each layer of the bioresorbable stent erodes. Methods of making the therapeutic layers within the bioresorbable sent are further disclosed. Sustained drug delivery reduces the risk of late and very late stent thrombosis.

The present invention relates to a process for producing a hot melt adhesive (HMA) material, preferably hot melt pressure sensitive adhesive (HMPSA) material, having a substantially tack-free coating comprising a novel moulding and spraying step, wherein said HMA material, preferably HMPSA material, can be easily handled, packed and transported for further use. In addition, the present invention relates to a corresponding device for producing a hot melt adhesive (HMA) material, preferably hot melt pressure sensitive adhesive (HMPSA) material, having a substantially tack-free coating.

The present invention relates to a process for producing a hot melt adhesive (HMA) material, preferably hot melt pressure sensitive adhesive (HMPSA) material, having a substantially tack-free coating comprising a novel moulding and spraying step, wherein said HMA material, preferably HMPSA material, can be easily handled, packed and transported for further use. In addition, the present invention relates to a corresponding device for producing a hot melt adhesive (HMA) material, preferably hot melt pressure sensitive adhesive (HMPSA) material, having a substantially tack-free coating.