The present patent application relates to a method of manufacturing a multilayered composite film comprising a step of co-extruding at least three layers (a), (b) and (c), of which the layer (a) forms an outward surface of the composite film; the layer (c) forms a surface of the composite film facing or coming in contact with a good to be packaged; and the layer (b) is disposed between the layer (a) and the layer (c). Further, the method includes a step of biaxial orientation of the composite film thus co-extruded. Therein, the layer (a) contains or consists of a thermoplastic resin. The layer (b) contains or consists of a polyvinylidene chloride (PVdC) resin. The layer (c) contains or consists of a resin, preferably sealable, in particular heat-sealable resin. Therein, any crosslinking of the composite film by means of radioactive radiation, in particular by means of beta, gamma, X-ray and/or electron irradiation, is omitted during the manufacturing of the composite film and/or thereafter.

The present patent application relates to a method of manufacturing a multilayered composite film comprising a step of co-extruding at least three layers (a), (b) and (c), of which the layer (a) forms an outward surface of the composite film; the layer (c) forms a surface of the composite film facing or coming in contact with a good to be packaged; and the layer (b) is disposed between the layer (a) and the layer (c). Further, the method includes a step of biaxial orientation of the composite film thus co-extruded. Therein, the layer (a) contains or consists of a thermoplastic resin. The layer (b) contains or consists of a polyvinylidene chloride (PVdC) resin. The layer (c) contains or consists of a resin, preferably sealable, in particular heat-sealable resin. Therein, any crosslinking of the composite film by means of radioactive radiation, in particular by means of beta, gamma, X-ray and/or electron irradiation, is omitted during the manufacturing of the composite film and/or thereafter.

A method includes hermetically sealing a medical device within a pouch, the pouch including peeling panels that are free from one another. The pouch is placed within a tray and the peeling panels are attached to unloading handles of the tray. The unloading handles are releasably coupled together. The method further includes simultaneously separating the unloading handles and the peeling panels to open the pouch and expose the medical device for removal thereof.

A rectangular-bottomed packaging bag (1) is a rectangular-bottomed packaging bag formed by folding a sheet material member and includes a rectangular shaped bottom (2) a front (3) and a rear (4) rising from two facing sides of the bottom (2), and a pair of sides (5) connecting the front (3) and the rear (4). The pair of sides (5) each include a first region (31) positioned on the front (3) side, a second region (32) positioned on the rear (4) side, a side joining portion (33) joining the first region (31) and the second region (32), and an inclined joining portion (34) inclined to the bottom (2) side from the side joining portion (33) toward one of the front (3) and the rear (4) and joining the sheet material member of the first region (31) and the second region (32) overlapping each other in a direction of thickness.

The press-through pack package of the invention has a covering material composed of a stretched film with at least one layer comprising a thermoplastic resin and an inorganic filler at 5 parts by weight with respect to 100 parts by weight of the thermoplastic resin.

A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

To provide a medication storage cell that can be easily opened by a person who cannot dexterously move his or her fingertips. A small-medication storage cell (12) is provided with an accommodating section (20) and an interlocking piece (22). The accommodating section (20) has an outlet for a medication (100). The outlet (30) is formed using a sheet (60) provided with an interlocking piece, and a cover sheet (62). The interlocking piece (22) has a base section (40) and a tip end section (42). At least a part of the base section (40) is separated from the surface of the accommodating section (20). The tip end section (42) is fastened to the accommodating section (20) in a bent state so that the cover sheet (62) and the sheet (60) provided with an interlocking piece close the outlet (30).

To provide a medication storage cell that can be easily opened by a person who cannot dexterously move his or her fingertips. A small-medication storage cell (12) is provided with an accommodating section (20) and an interlocking piece (22). The accommodating section (20) has an outlet for a medication (100). The outlet (30) is formed using a sheet (60) provided with an interlocking piece, and a cover sheet (62). The interlocking piece (22) has a base section (40) and a tip end section (42). At least a part of the base section (40) is separated from the surface of the accommodating section (20). The tip end section (42) is fastened to the accommodating section (20) in a bent state so that the cover sheet (62) and the sheet (60) provided with an interlocking piece close the outlet (30).

Heat-seal condition indicating packages include a first sealing substrate comprising a leuco dye and a second sealing substrate comprising a leuco dye developer. The packages may optionally include a leuco dye sensitizer which dissolves both the leuco dye and the leuco dye developer when melted. The packages further include a heat-seal produced between the first sealing substrate and the second seating substrate. The heat-seal comprises a reaction product of the leuco dye and the leuco dye developer. The reaction product may be colored, which may provide the heat-seal with a detectable optical characteristic. A magnitude of the optical characteristic may be proportion to the strength of the seal between the first and second seating substrates.