The invention provides a skin disinfectant for treating skin with eczema, preventing bacterial proliferation, and removing biofilm. Compositions of the invention include hypochlorous acid, acetic acid, water, and one or more additives or excipients. The formulation process removes metal ions, reduces ionic strength, controls pH, and reduces exposure to air, thus improving stability and lengthening shelf-life.

The invention provides a skin disinfectant for treating skin with eczema, preventing bacterial proliferation, and removing biofilm. Compositions of the invention include hypochlorous acid, acetic acid, water, and one or more additives or excipients. The formulation process removes metal ions, reduces ionic strength, controls pH, and reduces exposure to air, thus improving stability and lengthening shelf-life.

The use of powdered or gelled hypochlorous acid (HOCI) in the treatment or prevention of viral and bacterial infection is disclosed.

The use of powdered or gelled hypochlorous acid (HOCI) in the treatment or prevention of viral and bacterial infection is disclosed.

A system and associated method for producing an HOCl solution and an NaOH solution includes a generator operable for producing the HOCl and NaOH solutions utilizing electricity and a mixture of water and brine in an electrolysis cell. The generator includes a mechanical fixed flow restrictor (FFR) operable for controlling at least one of a pH of the HOCl solution and a free available chlorine (FAC) of the HOCl solution. The FFR includes an insert having a longitudinal fluid passageway. The length of the insert and the diameter of the fluid passageway are selected to control the pH of the HOCl solution and/or the FAC of the HOCl solution. The FFR is interchangeable so that the pH of the HOCl solution and/or the FAC of the HOCl solution can be precisely controlled.

A system and associated method for producing an HOCl solution and an NaOH solution includes a generator operable for producing the HOCl and NaOH solutions utilizing electricity and a mixture of water and brine in an electrolysis cell. The generator includes a mechanical fixed flow restrictor (FFR) operable for controlling at least one of a pH of the HOCl solution and a free available chlorine (FAC) of the HOCl solution. The FFR includes an insert having a longitudinal fluid passageway. The length of the insert and the diameter of the fluid passageway are selected to control the pH of the HOCl solution and/or the FAC of the HOCl solution. The FFR is interchangeable so that the pH of the HOCl solution and/or the FAC of the HOCl solution can be precisely controlled.

Provided is a method for preparing a hypochlorous acid aqueous solution by which a weakly acidic hypochlorous acid aqueous solution having a pH of about 3.5-7 can be obtained without substantially generating chlorine gas even immediately after regeneration or even with a new weakly acidic cation exchange resin. In a method for preparing a hypochlorous acid aqueous solution wherein an aqueous solution of hypochlorite is brought into contact with a weakly acidic cation exchanger to exchange a cation constituting the hypochlorite with hydrogen ions to increase the concentration of hypochlorous acid in the aqueous solution, a neutral salt solution of a strong acid and a strong base in an amount that may obtain the hypochlorous acid aqueous solution having a pH of at least 3.5 when the hypochlorite aqueous solution is brought into contact with the weakly acidic cation exchanger is brought into contact, prior to the contact between the hypochlorite aqueous solution and the weakly acidic cation exchanger, with a weakly acidic cation exchanger that has been regenerated or has not been substantially subjected to cation exchange.

Provided is a method for preparing a hypochlorous acid aqueous solution by which a weakly acidic hypochlorous acid aqueous solution having a pH of about 3.5-7 can be obtained without substantially generating chlorine gas even immediately after regeneration or even with a new weakly acidic cation exchange resin. In a method for preparing a hypochlorous acid aqueous solution wherein an aqueous solution of hypochlorite is brought into contact with a weakly acidic cation exchanger to exchange a cation constituting the hypochlorite with hydrogen ions to increase the concentration of hypochlorous acid in the aqueous solution, a neutral salt solution of a strong acid and a strong base in an amount that may obtain the hypochlorous acid aqueous solution having a pH of at least 3.5 when the hypochlorite aqueous solution is brought into contact with the weakly acidic cation exchanger is brought into contact, prior to the contact between the hypochlorite aqueous solution and the weakly acidic cation exchanger, with a weakly acidic cation exchanger that has been regenerated or has not been substantially subjected to cation exchange.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided having various concentrations for different tissue types and infection levels. Compositions may be provided in gel form, and may include nanoparticle encapsulated molecules for controlled release.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided having various concentrations for different tissue types and infection levels. Compositions may be provided in gel form, and may include nanoparticle encapsulated molecules for controlled release.