Patent classifications
C07C235/02
Materials and methods for suppressing and/or treating bone related diseases and symptoms
Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reducing resistance to the treatment, prevention, and diagnosis of diseases/symptoms induced by multiple myeloma. Embodiments include methods of treating a bone related disease, comprising the steps of: administering to a subject at least one therapeutically effective dose of a compound disclosed herein.
Tyrosine-based lipids for delivery of therapeutics
This disclosure provides a range of tyrosine amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
Tyrosine-based lipids for delivery of therapeutics
This disclosure provides a range of tyrosine amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
Imidazolyl tricyclic enones as antioxidant inflammation modulators
Disclosed herein are compounds of the formula: (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders associated with inflammation and cancer. ##STR00001##
Imidazolyl tricyclic enones as antioxidant inflammation modulators
Disclosed herein are compounds of the formula: (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders associated with inflammation and cancer. ##STR00001##
MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS
Various aspects and embodiments disclosed herein relate generally to the modelling, treatment, reducing resistance to the treatment, prevention, and diagnosis of diseases/symptoms induced by multiple myeloma. Embodiments include methods of treating a bone related disease, comprising the steps of: administering to a subject at least one therapeutically effective dose of a compound disclosed herein.
LIPIDS FOR DELIVERY OF THERAPEUTICS
This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
LIPIDS FOR DELIVERY OF THERAPEUTICS
This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
IMIDAZOLYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
Disclosed herein are compounds of the formula: (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders associated with inflammation and cancer.
##STR00001##
OXYGEN-ABSORBING COMPOUND, AND OXYGEN-ABSORBING ADHESIVE COMPOSITION AND OXYGEN-ABSORBING COATING AGENT COMPOSITION EACH USING SAME
An oxygen-absorbing compound has oxygen-absorbing properties and generates less odor. An oxygen-absorbing adhesive composition and a coating agent composition are produced using the oxygen-absorbing compound. The adhesive composition is used for forming an adhesive layer in a laminate for a packaging material, generates less odor, absorbs oxygen in a packaging bag or a packaging container to prevent the deterioration of a content in the packaging bag or the packaging container, and has an excellent balance among adhesion strength, the amount of generated odor and oxygen adsorption properties. The coating agent composition forms a coating layer for the surface of the laminate for a packaging material, generates less odor, and absorbs oxygen penetrating through the laminate or oxygen in a packaging bag or container. The oxygen-absorbing compound has one or two or more unsaturated five-membered rings that have a carbon-carbon double bond.