C07C271/26

MOISTURE-STABLE HOLOGRAPHIC MEDIA

The invention relates to novel compounds which are especially suitable for use as writing monomers in holographic media. The invention further provides a photopolymer and a holographic medium comprising the inventive compounds, and an optical display, a security document and a holographic optical element comprising an inventive holographic medium.

MOISTURE-STABLE HOLOGRAPHIC MEDIA

The invention relates to novel compounds which are especially suitable for use as writing monomers in holographic media. The invention further provides a photopolymer and a holographic medium comprising the inventive compounds, and an optical display, a security document and a holographic optical element comprising an inventive holographic medium.

Selective potassium channel agonists

Selective potassium channel agonists and methods of use thereof are disclosed. A compound, or a pharmaceutically acceptable salt thereof, having a formula I ##STR00001##
wherein R.sup.1 is H or optionally-substituted alkyl; R.sup.2 is optionally-substituted C.sub.1-C.sub.6 alkyl or optionally-substituted cyclopropyl; R.sup.3 and R.sup.4 are each independently H or optionally-substituted alkyl; R.sup.5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R.sup.6 and R.sup.7 are each independently H, optionally-substituted alkyl, or R.sup.6 and R.sup.7 together form a carbocycle; R.sup.8 is substituted phenyl or optionally-substituted pyridinyl, provided that if R.sup.8 is substituted phenyl, then R.sup.2 is optionally-substituted cyclopropyl; and R.sup.9, R.sup.10 and R.sup.11 are each independently H, halo, or optionally-substituted alkyl.

Selective potassium channel agonists

Selective potassium channel agonists and methods of use thereof are disclosed. A compound, or a pharmaceutically acceptable salt thereof, having a formula I ##STR00001##
wherein R.sup.1 is H or optionally-substituted alkyl; R.sup.2 is optionally-substituted C.sub.1-C.sub.6 alkyl or optionally-substituted cyclopropyl; R.sup.3 and R.sup.4 are each independently H or optionally-substituted alkyl; R.sup.5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R.sup.6 and R.sup.7 are each independently H, optionally-substituted alkyl, or R.sup.6 and R.sup.7 together form a carbocycle; R.sup.8 is substituted phenyl or optionally-substituted pyridinyl, provided that if R.sup.8 is substituted phenyl, then R.sup.2 is optionally-substituted cyclopropyl; and R.sup.9, R.sup.10 and R.sup.11 are each independently H, halo, or optionally-substituted alkyl.

SELECTIVE POTASSIUM CHANNEL AGONISTS

Selective potassium channel agonists and methods of use thereof are disclosed. A compound, or a pharmaceutically acceptable salt thereof, having a formula I

##STR00001##

wherein R.sup.1 is H or optionally-substituted alkyl; R.sup.2 is optionally-substituted C.sub.1-C.sub.6 alkyl or optionally-substituted cyclopropyl; R.sup.3 and R.sup.4 are each independently H or optionally-substituted alkyl; R.sup.5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R.sup.6 and R.sup.7 are each independently H, optionally-substituted alkyl, or R.sup.6 and R.sup.7 together form a carbocycle; R.sup.8 is substituted phenyl or optionally-substituted pyridinyl, provided that if R.sup.8 is substituted phenyl, then R.sup.2 is optionally-substituted cyclopropyl; and R.sup.9, R.sup.10 and R.sup.11 are each independently H, halo, or optionally-substituted alkyl.

SELECTIVE POTASSIUM CHANNEL AGONISTS

Selective potassium channel agonists and methods of use thereof are disclosed. A compound, or a pharmaceutically acceptable salt thereof, having a formula I

##STR00001##

wherein R.sup.1 is H or optionally-substituted alkyl; R.sup.2 is optionally-substituted C.sub.1-C.sub.6 alkyl or optionally-substituted cyclopropyl; R.sup.3 and R.sup.4 are each independently H or optionally-substituted alkyl; R.sup.5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R.sup.6 and R.sup.7 are each independently H, optionally-substituted alkyl, or R.sup.6 and R.sup.7 together form a carbocycle; R.sup.8 is substituted phenyl or optionally-substituted pyridinyl, provided that if R.sup.8 is substituted phenyl, then R.sup.2 is optionally-substituted cyclopropyl; and R.sup.9, R.sup.10 and R.sup.11 are each independently H, halo, or optionally-substituted alkyl.

Diazomethylation reagent and process for using it

The present invention relates compounds useful as reagents for the diazomethylation reaction, their preparation and the use thereof as reagents in a method for the diazomethylation reaction of aromatic substrates. It relates in particular to a compound of formula (I) wherein E is an electron withdrawing group. ##STR00001##

Diazomethylation reagent and process for using it

The present invention relates compounds useful as reagents for the diazomethylation reaction, their preparation and the use thereof as reagents in a method for the diazomethylation reaction of aromatic substrates. It relates in particular to a compound of formula (I) wherein E is an electron withdrawing group. ##STR00001##

DIAZOMETHYLATION REAGENT AND PROCESS FOR USING IT
20200010409 · 2020-01-09 ·

The present invention relates compounds useful as reagents for the diazomethylation reaction, their preparation and the use thereof as reagents in a method for the diazomethylation reaction of aromatic substrates. It relates in particular to a compound of formula (I) wherein E is an electron withdrawing group.

##STR00001##

DIAZOMETHYLATION REAGENT AND PROCESS FOR USING IT
20200010409 · 2020-01-09 ·

The present invention relates compounds useful as reagents for the diazomethylation reaction, their preparation and the use thereof as reagents in a method for the diazomethylation reaction of aromatic substrates. It relates in particular to a compound of formula (I) wherein E is an electron withdrawing group.

##STR00001##