Patent classifications
C07C311/27
High affinity beta lactamase inhibitors
Inhibitors of beta lactamases and their use in treating bacterial infections are disclosed.
High affinity beta lactamase inhibitors
Inhibitors of beta lactamases and their use in treating bacterial infections are disclosed.
2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use
Compounds according to Formula I are provided: ##STR00001##
and salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.13, A, X and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula I.
2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use
Compounds according to Formula I are provided: ##STR00001##
and salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.13, A, X and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula I.
Substituted alkyl diaryl derivatives, methods of preparation and uses
Compounds according to Formula I are provided: and salts thereof, wherein Q.sub.1, Q.sub.2, R.sub.3, R.sub.4, X, and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula (I).
Q.sub.2-XYCHR.sub.3CHR.sub.4-Q.sub.1(I)
Substituted alkyl diaryl derivatives, methods of preparation and uses
Compounds according to Formula I are provided: and salts thereof, wherein Q.sub.1, Q.sub.2, R.sub.3, R.sub.4, X, and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula (I).
Q.sub.2-XYCHR.sub.3CHR.sub.4-Q.sub.1(I)
2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE
Compounds according to Formula I are provided:
##STR00001##
and salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.13, A, X and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula I.