Patent classifications
C
CHEMISTRY; METALLURGY
Load children
C07
ORGANIC CHEMISTRY
Load children
C07C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
Load children
311/00
Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
Load children Filter patents View analytics View as hierarchy Open in page
C07C311/30
Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
Load children Filter patents View analytics View as hierarchy Open in page
C07C311/31
having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
Load children Filter patents View analytics View as hierarchy Open in page
C07C311/34
of an acyclic unsaturated carbon skeleton
Filter patents View analytics View as hierarchy Open in page

C07C311/34

Compounds for inhibiting the activity of SARS-COV-2 spike glycoprotein
11034655 · 2021-06-15 ·

The present invention relates to compounds of formula (I) and its analogues (II) and (III): in which R.sub.1-R.sub.14, X, Y, Z.sub.1-Z.sub.4 are in the Summary of the Invention; capable of inhibiting the activity of RBD of SARS-COV-2 in its “closed” conformation before it binds with the human ACE2 receptor. The invention further provides a process for the preparation of compounds of the invention. ##STR00001##