Patent classifications
C07C311/43
INHIBITORS OF HEPATITIS B VIRUS
The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.
M-phenylenediamine compound and method for producing polymer compound using same
An m-phenylenediamine compound is represented by the following General Formula (I), (II), or (III). ##STR00001##
R.sup.1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, or an aryl group. R.sup.2, R.sup.3, and R.sup.4 each represent an alkyl group. R.sup.5 and R.sup.6 each represent an alkyl group. X represents a chlorine atom or a bromine atom. A method for producing a polymer compound includes obtaining a polymer compound by using the m-phenylenediamine compound represented by General Formula (I) as a raw material.
M-phenylenediamine compound and method for producing polymer compound using same
An m-phenylenediamine compound is represented by the following General Formula (I), (II), or (III). ##STR00001##
R.sup.1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, or an aryl group. R.sup.2, R.sup.3, and R.sup.4 each represent an alkyl group. R.sup.5 and R.sup.6 each represent an alkyl group. X represents a chlorine atom or a bromine atom. A method for producing a polymer compound includes obtaining a polymer compound by using the m-phenylenediamine compound represented by General Formula (I) as a raw material.
NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME
An m-phenylenediamine compound is represented by the following General Formula (I), (II), or (III).
##STR00001##
R.sup.1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, or an aryl group. R.sup.2, R.sup.3, and R.sup.4 each represent an alkyl group. R.sup.5 and R.sup.6 each represent an alkyl group. X represents a chlorine atom or a bromine atom. A method for producing a polymer compound includes obtaining a polymer compound by using the m-phenylenediamine compound represented by General Formula (I) as a raw material.
NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME
An m-phenylenediamine compound is represented by the following General Formula (I), (II), or (III).
##STR00001##
R.sup.1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, or an aryl group. R.sup.2, R.sup.3, and R.sup.4 each represent an alkyl group. R.sup.5 and R.sup.6 each represent an alkyl group. X represents a chlorine atom or a bromine atom. A method for producing a polymer compound includes obtaining a polymer compound by using the m-phenylenediamine compound represented by General Formula (I) as a raw material.
METHODS OF TREATING CANCER
Phenylsulfonamido compounds that inhibit genome-wide hypomethylation and can be used to treat cancer, including melanoma, prostate cancer, pancreatic cancer, breast cancer, colon cancer, lung cancer, ovarian cancer, and glioblastoma, are provided.
3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF
Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula:
##STR00001##
The compounds are useful for treating inflammatory and autoimmune diseases.
3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF
Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula:
##STR00001##
The compounds are useful for treating inflammatory and autoimmune diseases.
3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF
Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula:
##STR00001##
The compounds are useful for treating inflammatory and autoimmune diseases.
WDR5-MYC inhibitors
Substituted N-phenyl sulfonamide compounds inhibit WDR5-MYC interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.