The present disclosure relates to prodrugs, double prodrugs, derivatives and analogues of 3-(methylamino)-2-((methylamino)methyl)propane-1-thiol. The compounds of this disclosure also relate to ##STR00001##
The use of these compounds as radio— and chemo—protectors is also described.

A process for upgrading brominated flame retardants comprises a) provision of a plastic comprising a flame retardant A consisting of a carbon-based chain substituted by at least two bromine atoms; b) recovery of a composition comprising said flame retardant A; c) bringing said composition comprising said flame retardant A into contact, in an organic solvent, with a compound A′ selected from the group consisting of Na2S2, K2S2, a potassium or sodium alkyl xanthate, and a compound of formula Y—SH in which Y is an alkali metal, an alkaline earth metal, a metal selected from rare earth metals, a —C(NH2)═NH unit or a —C(NR1R2)=NR3 unit; in order to form a mixture C comprising a compound B consisting of a carbon-based chain substituted by at least two —SH functional groups; and d) purification of the mixture C obtained and recovery of said compound B.

A process for upgrading brominated flame retardants comprises a) provision of a plastic comprising a flame retardant A consisting of a carbon-based chain substituted by at least two bromine atoms; b) recovery of a composition comprising said flame retardant A; c) bringing said composition comprising said flame retardant A into contact, in an organic solvent, with a compound A′ selected from the group consisting of Na2S2, K2S2, a potassium or sodium alkyl xanthate, and a compound of formula Y—SH in which Y is an alkali metal, an alkaline earth metal, a metal selected from rare earth metals, a —C(NH2)═NH unit or a —C(NR1R2)=NR3 unit; in order to form a mixture C comprising a compound B consisting of a carbon-based chain substituted by at least two —SH functional groups; and d) purification of the mixture C obtained and recovery of said compound B.

Disclosed are a light-emitting device and a method of manufacturing the same. The light-emitting device includes: a first electrode; a second electrode facing the first electrode; an emission layer between the first electrode and the second electrode and including a quantum dot including a first ligand bonded to a surface thereof; and a charge transport layer including an inorganic nanoparticle including a second ligand bonded to a surface thereof, wherein an interface between the emission layer and the charge transport layer includes a cross-link in which the first ligand on the surface of the quantum dot and the second ligand on the surface of the inorganic nanoparticle are linked by a cross-linking agent.

Disclosed are a light-emitting device and a method of manufacturing the same. The light-emitting device includes: a first electrode; a second electrode facing the first electrode; an emission layer between the first electrode and the second electrode and including a quantum dot including a first ligand bonded to a surface thereof; and a charge transport layer including an inorganic nanoparticle including a second ligand bonded to a surface thereof, wherein an interface between the emission layer and the charge transport layer includes a cross-link in which the first ligand on the surface of the quantum dot and the second ligand on the surface of the inorganic nanoparticle are linked by a cross-linking agent.

The present invention relates to polycyclic aromatic hydrocarbon-based compounds, for a molecular electronic device, enabling molecular rectification, and molecular electronic devices comprising a molecular layer formed by means of the compounds self-assembled on an electrode. The compounds according to the present invention can realize rectifying properties by being introduced between electrodes and thus enable a high rectification ratio by means of low voltage driving, and thus can be substituted for a silicon-based diode device and, more particularly, can be utilized for a wearable device, Bluetooth, an IoT enabling device and the like which require low voltage driving.

The present invention relates to polycyclic aromatic hydrocarbon-based compounds, for a molecular electronic device, enabling molecular rectification, and molecular electronic devices comprising a molecular layer formed by means of the compounds self-assembled on an electrode. The compounds according to the present invention can realize rectifying properties by being introduced between electrodes and thus enable a high rectification ratio by means of low voltage driving, and thus can be substituted for a silicon-based diode device and, more particularly, can be utilized for a wearable device, Bluetooth, an IoT enabling device and the like which require low voltage driving.

The present invention relates to a dynamic chemical network that mimics the transfer of information and ultimately produces a chemical response, for example a readable signal. More specifically, the invention discloses a dynamic system able to selectively sense a biologically-relevant analyte, such as cysteine, in its reduced or its oxidized form (cystine) in aqueous media and in a biofluid (such as urine) for diagnostic application. Due to this property, said dynamic system is useful for the detection of cysteine or its derivatives in biological fluids such as urine.

The present invention relates to a dynamic chemical network that mimics the transfer of information and ultimately produces a chemical response, for example a readable signal. More specifically, the invention discloses a dynamic system able to selectively sense a biologically-relevant analyte, such as cysteine, in its reduced or its oxidized form (cystine) in aqueous media and in a biofluid (such as urine) for diagnostic application. Due to this property, said dynamic system is useful for the detection of cysteine or its derivatives in biological fluids such as urine.

The present invention relates to a dynamic chemical network that mimics the transfer of information and ultimately produces a chemical response, for example a readable signal. More specifically, the invention discloses a dynamic system able to selectively sense a biologically-relevant analyte, such as cysteine, in its reduced or its oxidized form (cystine) in aqueous media and in a biofluid (such as urine) for diagnostic application. Due to this property, said dynamic system is useful for the detection of cysteine or its derivatives in biological fluids such as urine.