The present invention relates to a method of synthesising sulforaphane by reacting a compound of formula (A) with an oxidizing agent in an aqueous solvent and in the presence of a catalyst. The invention further provides a method of synthesising a stabilised complex of sulforaphane and cyclodextrin by mixing the sulforaphane prepared by the methodology defined herein with cyclodextrin in an aqueous solvent.

The present invention relates to a method of synthesising sulforaphane by reacting a compound of formula (A) with an oxidizing agent in an aqueous solvent and in the presence of a catalyst. The invention further provides a method of synthesising a stabilised complex of sulforaphane and cyclodextrin by mixing the sulforaphane prepared by the methodology defined herein with cyclodextrin in an aqueous solvent.

An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: ##STR00001##
wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.

An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: ##STR00001##
wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.

An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA):

##STR00001##

wherein R.sub.1 includes the structure of formula (IIA), (IIIA), or (IVA),

##STR00002##

wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R.sub.2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R.sub.3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N═C═S group.

An isothiocyanate functional surfactant, wherein the protonated form of the surfactant includes the structure of formula (IA):

##STR00001##

wherein R.sub.1 includes the structure of formula (IIA), (IIIA), or (IVA),

##STR00002##

wherein X includes an integer ranging from approximately 0 to approximately 20, wherein R.sub.2 comprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein R.sub.3 comprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N═C═S group.

The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers and/or activity modifiers.

The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers and/or activity modifiers.

The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms. One suitable isothiocyanate functional surfactant is represented by the following chemical structure: ##STR00001##

The present invention relates to methods, formulations, and compositions for the treatment of biofilms. In particular, the application discloses isothiocyanate functional surfactants either alone or combination with adjunct agents to treat biofilms. One suitable isothiocyanate functional surfactant is represented by the following chemical structure: ##STR00001##