Patent classifications
C07C335/26
ADAMANTANE-1-CARBONYL THIOUREA, AS P2X RECEPTOR ANTAGONIST
Present invention is directed to Adamantane-1-carbonyl thioureas of formula I,
##STR00001##
Wherein, R is selected from 2-OH, 3-OH, 4-OH, 3,5 diCl, 4-OH, 3-CF3, 5-Br, (2-Cl, pyridine-3-yl), 3-SO2NH2, 2-Cl, 5-NO2, 2-OCH3, 3-OCH3, 4-OCH3, 3,4-diOCH3, 4-Br, 2-Br,4-CH3, 2-CH3, 4-Br, Quinolin-8-yl, 2-Br-4-isopropyl, and 3-(Dimethylamino)propane-1-yl, and their use as P2X Receptor Antagonist for the treatment of inflammation, pain, osteoporosis, neurodegenerative disorders, spinal card injury, hypertension, or urinary incontinence.
ADAMANTANE-1-CARBONYL THIOUREA, AS P2X RECEPTOR ANTAGONIST
Present invention is directed to Adamantane-1-carbonyl thioureas of formula I,
##STR00001##
Wherein, R is selected from 2-OH, 3-OH, 4-OH, 3,5 diCl, 4-OH, 3-CF3, 5-Br, (2-Cl, pyridine-3-yl), 3-SO2NH2, 2-Cl, 5-NO2, 2-OCH3, 3-OCH3, 4-OCH3, 3,4-diOCH3, 4-Br, 2-Br,4-CH3, 2-CH3, 4-Br, Quinolin-8-yl, 2-Br-4-isopropyl, and 3-(Dimethylamino)propane-1-yl, and their use as P2X Receptor Antagonist for the treatment of inflammation, pain, osteoporosis, neurodegenerative disorders, spinal card injury, hypertension, or urinary incontinence.
METHODS FOR SELECTIVE LEACHING AND EXTRACTION OF PRECIOUS METALS IN ORGANIC SOLVENTS
The present application relates to methods for leaching and extraction of precious metals. For example, the present application relates to methods of leaching gold, palladium and/or platinum from a substance comprising gold, palladium and/or platinum (such as a gold-containing ore or a platinum group metal (PGM) concentrate) using an organic solvent that is water-miscible or partially water-miscible.
METHODS FOR SELECTIVE LEACHING AND EXTRACTION OF PRECIOUS METALS IN ORGANIC SOLVENTS
The present application relates to methods for leaching and extraction of precious metals. For example, the present application relates to methods of leaching gold, palladium and/or platinum from a substance comprising gold, palladium and/or platinum (such as a gold-containing ore or a platinum group metal (PGM) concentrate) using an organic solvent that is water-miscible or partially water-miscible.
AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE
The present invention relates to an improved process for the preparation of enzalutamide by conventional synthesis, which avoids utilization of microwave irradiation and noxious reagents. The present invention also relates to an improved process for preparation of 4-isothiocyanato-2-(trifluoromethyl) benzonitrile, which is an intermediate in the synthesis of Enzalutamide.
HERBICIDAL COMPOUNDS
The present invention relates to a compound of formula (I) wherein: wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11 and G are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are thought to be suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.
##STR00001##
HERBICIDAL COMPOUNDS
The present invention relates to a compound of formula (I) wherein: wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11 and G are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are thought to be suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.
##STR00001##
Methods for simultaneous leaching and extraction of precious metals
The present application relates to methods for the simultaneous leaching and extraction of precious metals. For example, the present application relates to methods of leaching and extracting gold and/or palladium from a substance comprising gold and/or palladium such as a gold and/or palladium-containing ore in one step using a compound of Formula I: (I).
Methods for simultaneous leaching and extraction of precious metals
The present application relates to methods for the simultaneous leaching and extraction of precious metals. For example, the present application relates to methods of leaching and extracting gold and/or palladium from a substance comprising gold and/or palladium such as a gold and/or palladium-containing ore in one step using a compound of Formula I: (I).
METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS
The present application relates to methods for the simultaneous leaching and extraction of precious metals. For example, the present application relates to methods of leaching and extracting gold and/or palladium from a substance comprising gold and/or palladium such as a gold and/or palladium-containing ore in one step using a compound of Formula I: (I)