A compound, composition, or method for treating cancer is disclosed. The compound (that can be used in the composition and/or method) can include

##STR00001##

or pharmaceutically acceptable salts or solvates thereof. R.sup.1a-R.sup.1d, R.sup.2-R.sup.3 (and R.sup.4 where applicable), and A---B can be as defined herein.

A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia): ##STR00001##
or pharmaceutically acceptable salts or solvates thereof, wherein R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.2, and R.sup.3 are as defined, and A----B is selected from CHCH, CHCH(CH.sub.2).sub.pCH.sub.2, or CH.sub.2CH.sub.2(CH.sub.2)pCH.sub.2, and where p is 1 or 2.

A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia): ##STR00001##
or pharmaceutically acceptable salts or solvates thereof, wherein R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.2, and R.sup.3 are as defined, and A----B is selected from CHCH, CHCH(CH.sub.2).sub.pCH.sub.2, or CH.sub.2CH.sub.2(CH.sub.2)pCH.sub.2, and where p is 1 or 2.

The present invention provides a method for preparing a resveratrol compound, and belongs to the technical field of organic synthesis. In the present invention, first alkoxy-substituted benzyl halide, alkoxy-substituted benzaldehyde and a metal catalyst are subjected to oxidative addition and reduction elimination reactions to obtain alkoxy-substituted diphenylethanone; and then the alkoxy-substituted diphenylethanone and a metal catalyst are subjected to reduction, trans elimination and selective debenzylation reactions under a hydrogen atmosphere to obtain the resveratrol compound. In the preparation method of the present invention, the hydrogenation reduction, trans elimination and selective debenzylation reactions can be achieved just by a one-pot process, where the reaction directly obtains a trans olefin, thereby avoiding the formation of a isomer; and also the reaction selectively catalyzes debenzylation to eliminate Lewis acids from the source, and has the advantage of a high yield. Therefore, this process is a green and environmentally friendly process. The experimental results show that, the products obtained by the preparation method as provided by the present invention are all trans olefins, with the purity being up to more than 99.5%, and each yield being greater than 80%.

The present invention provides a method for preparing a resveratrol compound, and belongs to the technical field of organic synthesis. In the present invention, first alkoxy-substituted benzyl halide, alkoxy-substituted benzaldehyde and a metal catalyst are subjected to oxidative addition and reduction elimination reactions to obtain alkoxy-substituted diphenylethanone; and then the alkoxy-substituted diphenylethanone and a metal catalyst are subjected to reduction, trans elimination and selective debenzylation reactions under a hydrogen atmosphere to obtain the resveratrol compound. In the preparation method of the present invention, the hydrogenation reduction, trans elimination and selective debenzylation reactions can be achieved just by a one-pot process, where the reaction directly obtains a trans olefin, thereby avoiding the formation of a isomer; and also the reaction selectively catalyzes debenzylation to eliminate Lewis acids from the source, and has the advantage of a high yield. Therefore, this process is a green and environmentally friendly process. The experimental results show that, the products obtained by the preparation method as provided by the present invention are all trans olefins, with the purity being up to more than 99.5%, and each yield being greater than 80%.

Disclosed is a novel method for extraction of Oxyresveratrol from Artocarpus hirsutus.

A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia):

##STR00001##

or pharmaceutically acceptable salts or solvates thereof, wherein R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.2, and R.sup.3 are as defined, and A----B is selected from CHCH, CHCH(CH.sub.2).sub.pCH.sub.2, or CH.sub.2CH.sub.2(CH.sub.2).sub.pCH.sub.2, and where p is 1 or 2.

A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia):

##STR00001##

or pharmaceutically acceptable salts or solvates thereof, wherein R.sup.1a, R.sup.1b, R.sup.1c, R.sup.1d, R.sup.2, and R.sup.3 are as defined, and A----B is selected from CHCH, CHCH(CH.sub.2).sub.pCH.sub.2, or CH.sub.2CH.sub.2(CH.sub.2).sub.pCH.sub.2, and where p is 1 or 2.

Prenylated stilbene compounds and the use of such compounds in the treatment of diseases and medical disorders, for example cancer, skin ageing, inflammation, bacterial or fungal infection and immunosuppression.

Prenylated stilbene compounds and the use of such compounds in the treatment of diseases and medical disorders, for example cancer, skin ageing, inflammation, bacterial or fungal infection and immunosuppression.