C07C405/0083

Treprostinil prodrugs

Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

TREPROSTINIL PRODRUGS

Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

Method for preparing treprostinil and intermediate therefor

The present invention relates to a cost-effective and efficient method for preparing treprostinil with high purity, and an intermediate therefor.

Crystals of intermediate for benzindene prostaglandins and methods for preparation thereof

Stable crystalline Form I and Form II of compound (I) and methods for preparation thereof are provided, which present advantages in storage, formulation, shipment and handling for commercial considerations.

TREPROSTINIL PRODRUGS

Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

METHOD FOR PREPARING TREPROSTINIL AND INTERMEDIATE THEREFOR

The present invention relates to a cost-effective and efficient method for preparing treprostinil with high purity, and an intermediate therefor.

Processes for preparing cyclopenta[b]naphthalenol derivatives and intermediates thereof
10106499 · 2018-10-23 · ·

Novel processes for preparing cyclopenta[b]naphthalenol derivatives of Formula 1 ##STR00001##
which are useful for the synthesis of corresponding benzindene prostaglandins are provided. The present invention also relates to novel intermediates prepared from the processes.