CB-7 exhibits a weak TLR7 inhibiting effect in normal mice. The present invention provides a novel compound with a stronger TLR7 inhibiting effect than CB-7, a pharmaceutically acceptable salt of said compound, or a prodrug of said compound or salt. The present invention also provides a drug for the prevention or treatment of diseases associated with the activation of TLR7, said drug including the aforementioned TLR7 activation inhibitor.

In order to provide a novel compound that has good solvent solubility, has high storage stability (dissolution stability) during refrigerated or frozen storage, and can be used as a crosslinking agent, a substituted trisphenol compound represented by formula (2) below is provided:

##STR00001##

In order to provide a novel compound that has good solvent solubility, has high storage stability (dissolution stability) during refrigerated or frozen storage, and can be used as a crosslinking agent, a substituted trisphenol compound represented by formula (2) below is provided:

##STR00001##

The invention provides compounds for use in inhibiting a microbial alternative oxidase (AOX) and/or cytochrome bc.sub.1 complex. The invention extends to the use of such inhibitors in agrochemicals and in pharmaceuticals, for treating microbial infections, including fungal infections.

Disclosed herein, inter alia, are methods of making polyketide compounds.

Disclosed herein, inter alia, are methods of making polyketide compounds.

##STR00001##

The present invention relates to novel fragrance compounds of general formula (I) which exhibit a Sandalwood-like fragrance and which are derivable from campholenic aldehyde derivates according to general formula (II). Furthermore, the present invention discloses compositions comprising one or more of the inventive fragrance compounds. The invention also relates to the use of such compounds or fragrance compositions comprising one or more of the compounds according to the invention as an odorant or or improving the fixation of a fragrance compound or a fragrance composition. Furthermore, the present invention refers to the use of such compounds or compositions for the preparation of a perfumed products as well as perfumed products as such.

The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH.sub.2CH.sub.2CH═CHCH.sub.2CH.sub.2OCH.sub.2OCH.sub.2R′ (1), R.sup.1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH.sub.3(CH.sub.2).sub.3CH═CH(CH.sub.2).sub.8CH═CHCH.sub.2CH.sub.2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).

The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH.sub.2CH.sub.2CH═CHCH.sub.2CH.sub.2OCH.sub.2OCH.sub.2R′ (1), R.sup.1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH.sub.3(CH.sub.2).sub.3CH═CH(CH.sub.2).sub.8CH═CHCH.sub.2CH.sub.2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).

A fluorine-containing ether compound represented by a formula (1) shown below.

R.sup.1—(O(CH.sub.2).sub.a).sub.b-[A]-[B]—O—CH.sub.2—R.sup.2—CH.sub.2—R.sup.3  (1)

(In the formula (1), R.sup.1 is an alkyl group which may have a substituent, or an organic group having at least one double bond or triple bond. Further, a represents an integer of 2 to 4, and b is 0 or 1. [A] is represented by a formula (2): —(OCH.sub.2CH(OH)CH.sub.2).sub.c— (wherein c is 1 or 2). [B] is represented by a formula (3): —(O(CH.sub.2).sub.eCH(OH)CH.sub.2).sub.d— (wherein d is 0 or 1, and e represents an integer of 2 to 4). However, the sum of c in the formula (2) and d in the formula (3) is 2. R.sup.2 is a perfluoropolyether chain. R.sup.3 is represented by a formula (4): —(OCH.sub.2CH(OH)CH.sub.2).sub.2—O—CH.sub.2(CH.sub.2).sub.fOH (wherein f represents an integer of 2 to 5).