There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.

##STR00001##

There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.

##STR00001##

Described are methods for preparing a deuterated aldehyde using with a photocatalyst and a hydrogen atom transfer agent in a H.sub.2O free solvent comprising D.sub.2O and an organic solvent under an inert gas. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions.

Described are methods for preparing a deuterated aldehyde using with a photocatalyst and a hydrogen atom transfer agent in a H.sub.2O free solvent comprising D.sub.2O and an organic solvent under an inert gas. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions.

A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX. the micro-interfacial unit is connected between the reactor and the circulating heat exchange device, and connected with an external feed pipe of the reactor, for crushing a gas phase material into micro bubbles with a diameter greater than or equal to 1 μm and less than 1 mm and for mixing the micro bubbles with a liquid phase material to form an emulsion at the exterior of the reactor before a reaction material enters each of the reaction zones inside the reactor.

A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX. the micro-interfacial unit is connected between the reactor and the circulating heat exchange device, and connected with an external feed pipe of the reactor, for crushing a gas phase material into micro bubbles with a diameter greater than or equal to 1 μm and less than 1 mm and for mixing the micro bubbles with a liquid phase material to form an emulsion at the exterior of the reactor before a reaction material enters each of the reaction zones inside the reactor.

A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX. the micro-interfacial unit is connected between the reactor and the circulating heat exchange device, and connected with an external feed pipe of the reactor, for crushing a gas phase material into micro bubbles with a diameter greater than or equal to 1 μm and less than 1 mm and for mixing the micro bubbles with a liquid phase material to form an emulsion at the exterior of the reactor before a reaction material enters each of the reaction zones inside the reactor.

A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX. the micro-interfacial unit is connected between the reactor and the circulating heat exchange device, and connected with an external feed pipe of the reactor, for crushing a gas phase material into micro bubbles with a diameter greater than or equal to 1 μm and less than 1 mm and for mixing the micro bubbles with a liquid phase material to form an emulsion at the exterior of the reactor before a reaction material enters each of the reaction zones inside the reactor.

A compound represented by the formula 1 ##STR00001##
wherein R.sub.1 is H, or when R.sub.2 and R.sub.3 is H, then R.sub.1 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; R.sub.2 is H, or when R.sub.1 and R.sub.3 is H, then R.sub.2 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; R.sub.3 is H, or when R.sub.1 and R.sub.2 is H, then R.sub.3 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; and R.sub.4 is methyl or a branched or linear, saturated or unsaturated, unsubstituted or substituted (optionally with cyclopropyl groups), C.sub.2-C.sub.7 alkyl or alkenyl residue, preferentially isobutyl, isoamyl.
Said compounds are useful as perfume ingredients in personal care and household care products.

A compound represented by the formula 1 ##STR00001##
wherein R.sub.1 is H, or when R.sub.2 and R.sub.3 is H, then R.sub.1 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; R.sub.2 is H, or when R.sub.1 and R.sub.3 is H, then R.sub.2 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; R.sub.3 is H, or when R.sub.1 and R.sub.2 is H, then R.sub.3 is CHR.sub.5CHR.sub.6CHO, CR.sub.5═CR.sub.6CHO or C(CH.sub.3)CHO, wherein R.sub.5, R.sub.6 each independently may represent H or methyl; and R.sub.4 is methyl or a branched or linear, saturated or unsaturated, unsubstituted or substituted (optionally with cyclopropyl groups), C.sub.2-C.sub.7 alkyl or alkenyl residue, preferentially isobutyl, isoamyl.
Said compounds are useful as perfume ingredients in personal care and household care products.