A catalyst molded body, a production method thereof and a method for preparing cyclic ketone using the same, including: (a) producing a mixed powder including a catalyst powder and a binder; (b) producing a slurry by mixing an aqueous alkali hydroxide solution with the mixed powder; and obtaining a catalyst molded body by molding and heat-treating the slurry.

A catalyst molded body, a production method thereof and a method for preparing cyclic ketone using the same, including: (a) producing a mixed powder including a catalyst powder and a binder; (b) producing a slurry by mixing an aqueous alkali hydroxide solution with the mixed powder; and obtaining a catalyst molded body by molding and heat-treating the slurry.

A catalyst molded body, a production method thereof and a method for preparing cyclic ketone using the same, including: (a) producing a mixed powder including a catalyst powder and a binder; (b) producing a slurry by mixing an aqueous alkali hydroxide solution with the mixed powder; and obtaining a catalyst molded body by molding and heat-treating the slurry.

The present invention relates to a novel method for photocatalytic oxidation of allylic C—H bonds present in alkenes containing at least three carbon atoms. In this newly disclosed method, such alkenes, when reacted with carbon dioxide (CO.sub.2) in an organic solvent containing a catalyst comprising of a supported molecular complex of transition metal ions under conditions of ambient temperature and pressure using a readily available household LED lamp, yield oxygenated products. The developed method represents a unique way to use CO.sub.2 as an oxygen transfer agent to unsaturated organic compounds along with the formation of CO as a co-product using light as an energy source.

The present invention relates to a novel method for photocatalytic oxidation of allylic C—H bonds present in alkenes containing at least three carbon atoms. In this newly disclosed method, such alkenes, when reacted with carbon dioxide (CO.sub.2) in an organic solvent containing a catalyst comprising of a supported molecular complex of transition metal ions under conditions of ambient temperature and pressure using a readily available household LED lamp, yield oxygenated products. The developed method represents a unique way to use CO.sub.2 as an oxygen transfer agent to unsaturated organic compounds along with the formation of CO as a co-product using light as an energy source.

The present invention relates to methods to use cyclohexan-1,2-dione (CHD) groups to attach labels, linkers, and other molecules to a target compound comprising a CHD-reactive group such as a guanidine, amidine, urea, thiourea and the like. Methods of the invention include milder conditions than those previously known for promoting reaction of CHD with CHD-reactive groups, which makes the methods suitable for use with base-sensitive compounds and complex biomolecules. Methods of the invention are especially useful for attaching linking and labeling groups to a peptide that comprises at least one arginine residue, and can also be used to link such peptides to other target molecules such as nucleic acids. The invention also provides CHD-containing conjugation reagents and compositions comprising CHD-containing intermediates, and precursors useful for making CHD-containing compounds that can be used in the methods of the invention.

The present invention relates to methods to use cyclohexan-1,2-dione (CHD) groups to attach labels, linkers, and other molecules to a target compound comprising a CHD-reactive group such as a guanidine, amidine, urea, thiourea and the like. Methods of the invention include milder conditions than those previously known for promoting reaction of CHD with CHD-reactive groups, which makes the methods suitable for use with base-sensitive compounds and complex biomolecules. Methods of the invention are especially useful for attaching linking and labeling groups to a peptide that comprises at least one arginine residue, and can also be used to link such peptides to other target molecules such as nucleic acids. The invention also provides CHD-containing conjugation reagents and compositions comprising CHD-containing intermediates, and precursors useful for making CHD-containing compounds that can be used in the methods of the invention.

The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.

The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.

Provided is a solid acid catalyst for use in oxidation of a substrate in the coexistence of oxygen and ozone (solid acid catalyst for oxygen-ozone-coexisting oxidation). The solid acid catalyst enables oxidation of the substrate with a high conversion. This solid acid catalyst for oxygen-ozone-coexisting oxidation is a solid acid catalyst for use in an oxidation reaction to oxidize a substrate (A) in the coexistence of oxygen and ozone. The solid acid catalyst includes a transition metal in the form of an elementary substance, a compound, or an ion, and a support supporting the transition metal. The support includes, at least in its surface, a strong acid or super strong acid having a Hammett acidity function (H.sub.0) of −9 or less. The support is preferably a pellet or particle made of a fluorinated sulfonic acid resin, or a support including a solid and a layer of a fluorinated sulfonic acid resin disposed on the solid.