The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.

The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.

The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.

The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.

The invention relates to a method for the preparation of cyclic compounds in the metathesis of olefins from acyclic dienes comprising terminal and/or non-terminal C═C double bonds; the invention also relates to the use of homogeneous ruthenium complexes and homogeneous ruthenium complexes deposited on a solid support as catalysts and/or pre-catalysts for the preparation of cyclic olefins in olefin metathesis reactions.

The invention relates to a method for the preparation of cyclic compounds in the metathesis of olefins from acyclic dienes comprising terminal and/or non-terminal C═C double bonds; the invention also relates to the use of homogeneous ruthenium complexes and homogeneous ruthenium complexes deposited on a solid support as catalysts and/or pre-catalysts for the preparation of cyclic olefins in olefin metathesis reactions.

The present invention discloses a new class of trans-cyclooctenes (TCOs), “a-TCOs,” that are prepared in high yield via stereocontrolled 1,2-additions of nucleophiles to trans-cyclooct-4-enone, which itself was prepared on large scale in two steps from 1,5-cyclooctadiene. Computational transition state models rationalize the diastereoselectivity of 1,2-additions to deliver a-TCO products, which were also shown to be more reactive than standard TCOs and less hydrophobic than even a trans-oxocene analog. Illustrating the favorable physicochemical properties of a-TCOs, a fluorescent TAMRA derivative in live HeLa cells was shown to be cell-permeable through intracellular Diels-Alder chemistry and to washout more rapidly than other TCOs.

The present invention discloses a new class of trans-cyclooctenes (TCOs), “a-TCOs,” that are prepared in high yield via stereocontrolled 1,2-additions of nucleophiles to trans-cyclooct-4-enone, which itself was prepared on large scale in two steps from 1,5-cyclooctadiene. Computational transition state models rationalize the diastereoselectivity of 1,2-additions to deliver a-TCO products, which were also shown to be more reactive than standard TCOs and less hydrophobic than even a trans-oxocene analog. Illustrating the favorable physicochemical properties of a-TCOs, a fluorescent TAMRA derivative in live HeLa cells was shown to be cell-permeable through intracellular Diels-Alder chemistry and to washout more rapidly than other TCOs.

The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.

The present invention relates to the field of perfumery. More particularly, it concerns malodor masking compositions and/or ingredients, as well as method for counteracting or masking malodors and perfuming compositions having odor masking properties.