C07C49/687

PROCESS FOR PREPARING PERFUMING INTERMEDIATE
20230095887 · 2023-03-30 ·

The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) by a cross metathesis reaction. Said compound of formula (I) is valuable new chemical intermediate for producing perfuming ingredients and is also part of the present invention.

PROCESS FOR PREPARING PERFUMING INTERMEDIATE
20230095887 · 2023-03-30 ·

The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) by a cross metathesis reaction. Said compound of formula (I) is valuable new chemical intermediate for producing perfuming ingredients and is also part of the present invention.

PROCESS FOR PREPARING PERFUMING INTERMEDIATE
20230095887 · 2023-03-30 ·

The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) by a cross metathesis reaction. Said compound of formula (I) is valuable new chemical intermediate for producing perfuming ingredients and is also part of the present invention.

Method for Fluoroalkylation of Enamines

The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

Method for Fluoroalkylation of Enamines

The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

Method for fluoroalkylation of enamines

The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

Method for fluoroalkylation of enamines

The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

Anti-fungal compounds

The present disclosure provides compounds of the formula (I), (II), (III), wherein the variables are as defined herein for use in the treatment of fungal infections. In some embodiments, the fungal infection is an infection of Cryptococcus neojormans fungus. Also provided herein are compositions comprising a compound of formula I, II, or III and a second anti-fungal agent. ##STR00001##

Anti-fungal compounds

The present disclosure provides compounds of the formula (I), (II), (III), wherein the variables are as defined herein for use in the treatment of fungal infections. In some embodiments, the fungal infection is an infection of Cryptococcus neojormans fungus. Also provided herein are compositions comprising a compound of formula I, II, or III and a second anti-fungal agent. ##STR00001##

PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE

A method for producing a fluoromethyl derivative represented by formula (1), the method including step A of reacting an alkene compound represented by formula (2) with a fluorine source represented by formula MF.sub.n, in the presence of a hypervalent-iodine aromatic compound (1a), or in the presence of an aromatic iodine compound (1b) and an oxidant (A) to fluorinate the alkene compound.

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