An esterification process that uses an acetic acid composition from a wood acetylation process as a reactant. Even though the acetic acid composition contains impurities, such as ethyl acetate, methyl acetate, acetaldehyde, acetone, terpenes and/or terpenes derivatives, the impurities do not adversely affect the quality of the ether-ester products. This process can be economically advantageous by using cheaper acetic acid—one sourced directly from a wood acetylation process.

An esterification process that uses an acetic acid composition from a wood acetylation process as a reactant. Even though the acetic acid composition contains impurities, such as ethyl acetate, methyl acetate, acetaldehyde, acetone, terpenes and/or terpenes derivatives, the impurities do not adversely affect the quality of the ether-ester products. This process can be economically advantageous by using cheaper acetic acid—one sourced directly from a wood acetylation process.

A method of processing an aqueous hemicellulosic stream containing lignin, comprising: (a) contacting an aqueous hemicellulosic stream containing lignin with a C.sub.3-8 alkyl alcohol at elevated temperature and acidic pH; (b) separating the reaction mixture obtained from step (a) into an aqueous phase containing hemicellulose-derived monosaccharide and an organic phase containing C.sub.3-8 alkyl alcohol; (c) concentrating the organic phase obtained from step (b) to remove at least some C.sub.3-8 alkyl alcohol; (d) treating the residue from step (c) with water or an aqueous medium having an alkaline pH; and (e) recovering C.sub.3-8 alkyl alcohol from the product of step (d).

A method of processing an aqueous hemicellulosic stream containing lignin, comprising: (a) contacting an aqueous hemicellulosic stream containing lignin with a C.sub.3-8 alkyl alcohol at elevated temperature and acidic pH; (b) separating the reaction mixture obtained from step (a) into an aqueous phase containing hemicellulose-derived monosaccharide and an organic phase containing C.sub.3-8 alkyl alcohol; (c) concentrating the organic phase obtained from step (b) to remove at least some C.sub.3-8 alkyl alcohol; (d) treating the residue from step (c) with water or an aqueous medium having an alkaline pH; and (e) recovering C.sub.3-8 alkyl alcohol from the product of step (d).

Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

Disclosed are 1,3-Dioxoindene derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The 1,3-Dioxoindene derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media.

The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. In particular, the chemical entities of such synthetic diterpene compounds in the manufacture of a medicament is for the treatment of tumors or cancers.

A long life catalyst is provided that is conveniently and inexpensively capable of being produced and that is highly active and has inhibited metal leakage. According to aspects of the present invention, a catalyst is provided that includes: a polymer including a plurality of first structural units and a plurality of second structural units; and metal acting as a catalytic center, wherein at least part of the metal is covered with the polymer, each of the plurality of first structural units has a first atom constituting a main chain of the polymer and a first substituent group bonded to the first atom, a second atom included in each of the plurality of second structural units is bonded to the first atom, and the second atom is different from the first atom, or at least one of all substituent groups on the second atom is different from the first substituent group.

A long life catalyst is provided that is conveniently and inexpensively capable of being produced and that is highly active and has inhibited metal leakage. According to aspects of the present invention, a catalyst is provided that includes: a polymer including a plurality of first structural units and a plurality of second structural units; and metal acting as a catalytic center, wherein at least part of the metal is covered with the polymer, each of the plurality of first structural units has a first atom constituting a main chain of the polymer and a first substituent group bonded to the first atom, a second atom included in each of the plurality of second structural units is bonded to the first atom, and the second atom is different from the first atom, or at least one of all substituent groups on the second atom is different from the first substituent group.

A high-purity alcohol compound can be obtained by a method comprising passing a solution containing an ester compound and methanol and/or ethanol through a column packed with an anion exchange resin having methoxide and/or ethoxide as a counter anion to generate a methyl ester and/or ethyl ester, and distilling off the methyl ester and/or ethyl ester together with the methanol and/or ethanol.