The invention relates to a method for producing polyol esters, especially polyglycerol esters, of 3-oxobutyric acid, as well as the products thus obtained and their use.

The invention relates to a method for producing optionally functionalized acyl-capped (acyl-blocked) 3-hydroxybutyric acids and their salts and esters as well as to the products thus obtained and their use.

When a healthy and balanced diet is not achieved, nutritional supplements are used to help deal with the resulting health issues and enhance the body's performance. Two compounds of interest in this research, ketone bodies and β-Hydroxy β-Methylbutyrate (HMB) have been used for dealing with the side effects of various health conditions including muscle mass loss and insufficient food intake. Although these molecules have been used extensively as supplements, no supplement was found which combined the properties of both ketone bodies and HMB. This project was conceived to create a novel category of molecules that combine the properties of both ketone bodies and HMB that can be used as supplements for treating a wide range of health-related issues. Acetoacetate and isopentyldiol were used as the sources of ketone bodies and HMB, respectively. Six novel compounds were synthesized using transesterification of acetoacetate and isopentyldiol. Some of the developed reaction procedures were versatile as they could be performed under a variety of parameters such as solventless, catalyst-free, and mild conditions. Immobilized enzymes and chemicals were used to generate new compounds under greener parameters. The compounds that were isolated were characterized using GCMS, H NMR, and FTIR instrumentation. In summary, the goal of this research project was to design and synthesize novel ketone body analogs.

The invention discloses the use of a short path evaporator for decolorization of colorized acetoacetylated ethylene glycol.

The invention discloses the use of a short path evaporator for decolorization of colorized acetoacetylated ethylene glycol.

A solution containing a diketone compound having an alkoxy group, a dialkylzinc represented by general formula (1) and/or a partial hydrolysate of the dialkylzinc, and a solvent is described. A method for producing a zinc oxide thin film involves applying the dialkylzinc solution or a solution containing a dialkylzinc partial hydrolysate to a base material.
ZnR.sup.10.sub.2  (1)
In the formula, R.sup.10 is a C.sub.1-6 linear or branched alkyl group. The solution containing dialkylzinc or dialkylzinc partial hydrolysate can be handled in air, making it possible to form a transparent thin film having high adhesiveness to a substrate even with film formation in air.

The invention discloses a method for preparation of an acetoacetylated polyol by reaction of a polyol with deketene in the presence of a base and in the absence of a solvent.

The invention discloses a method for preparation of an acetoacetylated polyol by reaction of a polyol with deketene in the presence of a base and in the absence of a solvent.

When a healthy and balanced diet is not achieved, nutritional supplements are used to help deal with the resulting health issues and enhance the body's performance. The present invention relates to a novel category of molecules that combine the properties of both ketone bodies and β-Hydroxy β-Methylbutyrate (HMB) that can be used as supplements for treating a wide range of health-related issues. Acetoacetate and β-Hydroxybutrate along with isopentyldiol were used as the sources of ketone bodies and HMB, respectively. The present invention provides a method of synthesis for a new group of compounds that incorporate the properties found in acetoacetate and 3-hydroxybutyrate molecules with that of β-hydroxy β-methylbutyrate.

The invention discloses a method for preparation of an acetoacetylated polyol by reaction of a polyol with deketene in the presence of a base and in the absence of a solvent.