The present invention provides a polymer composition comprising a polymer and an antioxidant comprising a diarylamine-based compound represented by General Formula (1): ##STR00001##
where, in General Formula (1), A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent.

The present invention provides a polymer composition comprising a polymer and an antioxidant comprising a diarylamine-based compound represented by General Formula (1): ##STR00001##
where, in General Formula (1), A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent.

The present invention provides compounds of formula (I),

##STR00001##

wherein:

R.sub.1 is unsubstituted C.sub.1-C.sub.6 alkyl;

L.sub.a is substituted or unsubstituted C.sub.1-C.sub.6 alkyl linker, substituted or unsubstituted C.sub.3-C.sub.10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and

R.sub.2 and R.sub.3 are each, independently, H, substituted or unsubstituted C.sub.1-C.sub.6 alkyl, or substituted or unsubstituted C.sub.6-C.sub.10aryl;

or alternatively, R.sub.2 and R.sub.3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S.

The invention also provides pharmaceutical compositions and methods for treating neurological diseases, such as multiple sclerosis.

The present invention provides compounds of formula (I),

##STR00001##

wherein:

R.sub.1 is unsubstituted C.sub.1-C.sub.6 alkyl;

L.sub.a is substituted or unsubstituted C.sub.1-C.sub.6 alkyl linker, substituted or unsubstituted C.sub.3-C.sub.10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and

R.sub.2 and R.sub.3 are each, independently, H, substituted or unsubstituted C.sub.1-C.sub.6 alkyl, or substituted or unsubstituted C.sub.6-C.sub.10aryl;

or alternatively, R.sub.2 and R.sub.3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S.

The invention also provides pharmaceutical compositions and methods for treating neurological diseases, such as multiple sclerosis.

The present invention provides a diarylamine-based compound represented by General Formula (1): ##STR00001##
(where A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent).

The present invention provides a diarylamine-based compound represented by General Formula (1): ##STR00001##
(where A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent).

The purpose of the present invention is to provide a method for producing a pyrrole-imidazole (poly)amide compound with the rapidly improved conversion rates, high yield and high reproducibility in the reaction forming an amide bond between a carboxy group binding to a pyrrole and an amino group binding to an imidazole. A method for producing a pyrrole-imidazole (poly)amide by reacting an aminoimidazole carboxylic acid derivative with a pyrrolecarboxylic acid derivative in the presence of a heterocyclic aromatic compound as a solvent.

The present invention provides a polymer composition comprising a polymer and an antioxidant comprising a diarylamine-based compound represented by General Formula (1):

##STR00001##

where, in General Formula (1), A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent.

The present invention provides a polymer composition comprising a polymer and an antioxidant comprising a diarylamine-based compound represented by General Formula (1):

##STR00001##

where, in General Formula (1), A.sup.1 and A.sup.2 each independently represent a C.sub.6 to C.sub.18 arylene group which may have a substituent, and A.sup.3 and A.sup.4 each independently represent an organic group having a cyclic imide structure which may have a substituent.

The present invention provides compounds of formula (I), ##STR00001##
wherein: R.sub.1 is unsubstituted C.sub.1-C.sub.6 alkyl; L.sub.a is substituted or unsubstituted C.sub.1-C.sub.6 alkyl linker, substituted or unsubstituted C.sub.3-C.sub.10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and R.sub.2 and R.sub.3 are each, independently, H, substituted or unsubstituted C.sub.1-C.sub.6 alkyl, or substituted or unsubstituted C.sub.6-C.sub.10 aryl; or alternatively, R.sub.2 and R.sub.3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S. The invention also provides pharmaceutical compositions and methods for treating neurological diseases, such as multiple sclerosis.