C07D237/26

AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES

The present disclosure relates to azabicyclyl-substituted heterocyclic compounds of formula (I), wherein A.sup.1, A.sup.2, m, R.sup.3, R.sup.4, R.sup.5, L, R.sup.6, T, the ring Y, p, R.sup.7 and Q have the meanings as defined in the specification, to compositions comprising such compounds, to processes and intermediates for their preparation as well as the uses thereof for controlling phytopathogenic microorganisms, such as phytopathogenic fungi.

##STR00001##

Fluorescent detection of amines and hydrazines and assaying methods thereof
11530352 · 2022-12-20 · ·

Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.

Fluorescent detection of amines and hydrazines and assaying methods thereof
11530352 · 2022-12-20 · ·

Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.

Iridium complexes and their applications, as well as organic electroluminescent devices
11502260 · 2022-11-15 · ·

Irridium complexes with molecular formula of L.sub.3Ir, together with application thereof and organic electroluminescent devices, wherein Ir is the central metal atom and L is a ligand. The structure of these complexes is of the following formula (I): ##STR00001## Ar is selected from substituted or unsubstituted aryl groups with 6 to 30 carbon atoms, and substituted or unsubstituted heterocyclic aryl groups with 4 to 30 carbon atoms. R1 to R7 are each independently selected from atoms or groups described herein. The substituent group on above-mentioned Ar or R1 to R7 is independently selected from F, Cl, Br, I, CHO, CN, substituted or unsubstituted alkyl or cycloalkyl groups with 1 to 30 carbon atoms, fluoroalkyl groups, alkoxy groups, and thioalkoxy groups.

METHODS FOR CELL IMAGING
20230098031 · 2023-03-30 ·

The present application provides a compound of Formula (A), or a pharmaceutically acceptable salt thereof, wherein R.sup.1, L.sup.1, n, L.sup.2, m, L.sup.3, p, Y.sup.2, and Y.sup.3 are as described herein. Methods of using the compound of Formula (A) to prepare an antibody conjugate, and methods of using these conjugates for cellular imaging are also described.

##STR00001##

Labile esters of agrochemicals for controlled release and reduction of off-site movement
11465960 · 2022-10-11 · ·

The present invention relates to esters of carboxylic acid agrochemicals comprising a labile protecting group and having formula (I). Certain of the esters of carboxylic acid agrochemicals do not undergo hydrolysis to a significant degree in the dark, but are cleaved to regenerate the parent carboxylic acid agrochemical when exposed to light. Others of the esters of carboxylic acid agrochemicals undergo hydrolysis under both light and dark conditions. The present invention further relates to methods for the controlled release of a carboxylic acid agrochemicals, and to methods of controlling unwanted plants comprising applying to the unwanted plants an ester of a carboxylic acid agrochemical.

Labile esters of agrochemicals for controlled release and reduction of off-site movement
11465960 · 2022-10-11 · ·

The present invention relates to esters of carboxylic acid agrochemicals comprising a labile protecting group and having formula (I). Certain of the esters of carboxylic acid agrochemicals do not undergo hydrolysis to a significant degree in the dark, but are cleaved to regenerate the parent carboxylic acid agrochemical when exposed to light. Others of the esters of carboxylic acid agrochemicals undergo hydrolysis under both light and dark conditions. The present invention further relates to methods for the controlled release of a carboxylic acid agrochemicals, and to methods of controlling unwanted plants comprising applying to the unwanted plants an ester of a carboxylic acid agrochemical.

SMARCA INHIBITORS AND USES THEREOF
20230103415 · 2023-04-06 ·

The present invention provides compounds, compositions thereof, and methods of using the same.

Cleavable tetrazine used in bio-orthogonal drug activation

Disclosed is an advancement in provoked chemical cleavage. Thereby the invention provides the use of a diene as a chemically cleavable group attached to a Construct, and the use of a dienophile to provoke the release of the Construct by allowing the diene to react with a dienophile capable of undergoing an inverse electron demand Diels Alder reaction with the diene. The invention includes a kit for releasing a Construct C.sup.A bound to a Trigger T.sup.R, the kit having a tetrazine and a dienophile, wherein the Trigger is the tetrazine. The invention also includes the use of the formation of a pyridazine by reacting a tetrazine having a Construct C.sup.A bound thereto and a dienophile, as a chemical tool for the release, in a chemical, biological or physiological environment, of the Construct.

FLUORESCENT DETECTION OF AMINES AND HYDRAZINES AND ASSAYING METHODS THEREOF
20230139797 · 2023-05-04 ·

Provided herein are processes for preparing fluorescent 1-cyano-2-substituted isoindole compounds or N-substituted phthalazinium compounds, comprising reacting an aromatic dialdehyde or aromatic aldehyde-ketone compound with a material that contains primary amino or hydrazine groups, and assaying methods involving the processes thereof.