Patent classifications
C
CHEMISTRY; METALLURGY
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C07
ORGANIC CHEMISTRY
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C07D
HETEROCYCLIC COMPOUNDS
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241/00
Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
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C07D241/02
not condensed with other rings
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C07D241/10
having three double bonds between ring members or between ring members and non-ring members
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C07D241/14
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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C07D241/24
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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C07D241/26
with nitrogen atoms directly attached to ring carbon atoms
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C07D241/28
in which said hetero-bound carbon atoms have double bonds to oxygen, sulfur or nitrogen atoms
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C07D241/34
(Amino-pyrazine carbonamido) guanidines
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C07D241/34

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide
11578042 · 2023-02-14 · ·

The present invention relates to the compound of the formula: ##STR00001##
or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide
11578042 · 2023-02-14 · ·

The present invention relates to the compound of the formula: ##STR00001##
or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.

ANTIVIRAL COMPOUNDS AND METHODS
20170260147 · 2017-09-14 · ·

The invention relates to compounds having antiviral and methods utilizing the compounds to treat viral infections.

ANTIVIRAL COMPOUNDS AND METHODS
20170260147 · 2017-09-14 · ·

The invention relates to compounds having antiviral and methods utilizing the compounds to treat viral infections.

Antiviral compounds and methods
11192863 · 2021-12-07 · ·

The invention relates to compounds having antiviral and methods utilizing the compounds to treat viral infections.

Antiviral compounds and methods
11192863 · 2021-12-07 · ·

The invention relates to compounds having antiviral and methods utilizing the compounds to treat viral infections.

3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE
20210024471 · 2021-01-28 · ·

The present invention relates to the compound of the formula:

##STR00001##

or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.

3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL)CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE
20210024471 · 2021-01-28 · ·

The present invention relates to the compound of the formula:

##STR00001##

or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
10526292 · 2020-01-07 · ·

Sodium channel blockers represented by the formula: ##STR00001##
are provided where the structural variables are defined herein. The invention also includes a variety of compositions, combinations and methods of treatment using these inventive sodium channel blockers.

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
10526292 · 2020-01-07 · ·

Sodium channel blockers represented by the formula: ##STR00001##
are provided where the structural variables are defined herein. The invention also includes a variety of compositions, combinations and methods of treatment using these inventive sodium channel blockers.