A luminescent device, a manufacturing method thereof, and a display apparatus, the luminescent device may avoid a fluorescence quenching problem of the quantum dot light-emitting layer due to the influence of the electron transport layer. The luminescent device includes: an anode, a quantum dot light-emitting layer, an electron transport layer, and a cathode in a stacked arrangement; the electron transport layer includes inorganic oxide nanoparticles and a porous frame structure, and the inorganic oxide nanoparticles are anchored in pores of the porous frame structure; the porous frame structure is configured to be formed by ligand reaction; a general structural formula of the ligand includes: A-X-Q; A is a coordinating group, and is configured to coordinate with the inorganic oxide nanoparticles, X is a regulator group, and is configured to increase or decrease an electron mobility, and Q is a frame group, and is configured to form a frame structure.