C07D277/22

ANALOGS OF PROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) AGONISTS AND METHODS OF USING THE SAME

Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.

Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same

Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.

Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same

Peroxisome proliferator activated receptor (PPAR) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.

Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element

The present disclosure provides an organic light emitting element which has a pair of electrodes and an organic compound layer disposed therebetween and in which the organic compound layer contains an organic compound represented by the following general formula [1], ##STR00001##
wherein in the formula [1], Ar.sub.1 and Ar.sub.2 each independently represent an aromatic hydrocarbon group or a heteroaromatic ring group, R.sub.1 to R.sub.4 are each independently selected from a hydrogen atom or a substituent, R.sub.1 and R.sub.2 and R.sub.3 and R.sub.4 each may form a benzene ring, wherein the benzene ring may have at least one substituent.

Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element

The present disclosure provides an organic light emitting element which has a pair of electrodes and an organic compound layer disposed therebetween and in which the organic compound layer contains an organic compound represented by the following general formula [1], ##STR00001##
wherein in the formula [1], Ar.sub.1 and Ar.sub.2 each independently represent an aromatic hydrocarbon group or a heteroaromatic ring group, R.sub.1 to R.sub.4 are each independently selected from a hydrogen atom or a substituent, R.sub.1 and R.sub.2 and R.sub.3 and R.sub.4 each may form a benzene ring, wherein the benzene ring may have at least one substituent.

NOVEL COMPOUNDS

The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haematopoietic system including the haematologic system in human and veterinary medicine.

##STR00001##

SULFUR AND AMIDE TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES THEREFOR

The present disclosure provides inhibitors of microorganisms including viruses and fungi of the formula (I) or (II) wherein the variables are defined herein. Also provided are methods of treatment using these agents in the treatment of infections of microorganisms such as viruses and fungi.

##STR00001##

SULFUR AND AMIDE TROPOLONE INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES THEREFOR

The present disclosure provides inhibitors of microorganisms including viruses and fungi of the formula (I) or (II) wherein the variables are defined herein. Also provided are methods of treatment using these agents in the treatment of infections of microorganisms such as viruses and fungi.

##STR00001##

1,4-diphenyl-1H-imidazole and 2,4-diphenylthiazole derivatives and preparation method therefor and use thereof

Provided are 1,4-diphenyl-1H-imidazole and 2,4-diphenylthiazole derivatives having a structure represented by Formula I, a preparation method therefor and uses thereof: ##STR00001##
wherein R.sub.1 is any one of H, OH, and OCH.sub.3, R.sub.2 is any one of H, NO.sub.2, CH.sub.3, CF.sub.3, SO.sub.2CH.sub.3, COOCH.sub.3, or CONHCH.sub.3, R.sub.3 is any one of H, NO.sub.2, OCH.sub.3, or CF.sub.3, R.sub.4 is selected from H, CF.sub.3, or Cl, R.sub.5 is any one of H, Cl, CF.sub.3, or NHCH.sub.3, and R.sub.6 is any one of OCF.sub.3, CF.sub.3, or CN; V is either C or N, W is either CH or N, X is a C atom, Y is either CH or N, and Z is either CH or S. This compound can be used in preparation of anti-inflammatory adjuvants, TLR1 or TLR2 agonists, and anti-tumor agents and for regulating the activity activation level of TLR1 and TLR2 alkaline phosphatases in vitro and in vivo.

ONIUM SALT OF NITROGEN-CONTAINING HETEROARYL COMPOUND AND PEST CONTROL AGENT

A compound represented by formula (I) or formula (II) has a pest control effect. (In the formulae, Q.sup.1 represents a pyrazine ring or the like; G.sup.1 represents a nitrogen atom or a carbon atom; X.sup.1 represents an alkyl group or the like; m represents the number of X.sup.1 moieties; A represents an oxygen atom or the like; Y represents a single bond or the like; Q.sup.2 represents a benzene ring or the like; X.sup.2 represents an alkyl group, an aryl group or the like; X.sup.3 represents a halogeno group or the like; n represents the number of X.sup.3 moieties; Z.sup.q- represents a counter ion; and q represents 1 or 2.)

##STR00001##