Patent classifications
C07D309/32
Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds
The present invention relates to compounds of Formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants. ##STR00001##
3-methylideneoxan-4-one compounds and substituted derivatives thereof as inhibitors of telomerase
Disclosed are 3-methylideneoxan-4-one compounds, derivatives thereof, and methods of their synthesis and methods of their use in treating a disease or disorder in a subject in need thereof, such as diseases and disorders that are associated with telomerase activity such as cancer. The disclosed compounds may be formulated in a pharmaceutical composition for treating diseases and disorders that are associated with telomerase activity such as cancer.
3-methylideneoxan-4-one compounds and substituted derivatives thereof as inhibitors of telomerase
Disclosed are 3-methylideneoxan-4-one compounds, derivatives thereof, and methods of their synthesis and methods of their use in treating a disease or disorder in a subject in need thereof, such as diseases and disorders that are associated with telomerase activity such as cancer. The disclosed compounds may be formulated in a pharmaceutical composition for treating diseases and disorders that are associated with telomerase activity such as cancer.
INTEGRATED PROCESS FOR GENERATING ACID ANHYDRIDES
Provided is a first process of producing an anhydride of an organic mono-acid comprising performing a transanhydridization reaction of an organic mono-acid and a thermally regenerable anhydride to produce the anhydride of the organic mono-acid and an acid of the thermally regenerable anhydride, wherein at least one of the organic mono-acid and thermally regenerable anhydride is provided by a preprocess that is integrated with the first process. An anhydride production system that is integrated with at least one preprocess, a wood acetylation process coupled to an acetic anhydride production process, a process of supplying an acetic acid reactant feed to a transanhydridization reaction unit, and an integrated wood acetylation and anhydride production system also are provided.
Compounds for treating neurodegenerative disorders
The invention relates to compounds of formula (I), their method of synthesis as well as their use to treat neurodegenerative disorders. ##STR00001##
CANNABINOID DERIVATIVES
The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such as pain, ADHD/ADD, alcohol use disorder, anxiety disorder, and dementias.
CANNABINOID DERIVATIVES
The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such as pain, ADHD/ADD, alcohol use disorder, anxiety disorder, and dementias.
3-Methylideneoxan-4-One Compounds and Substituted Derivates Thereof as Inhibitors of Telomerase
Disclosed are 3-methylideneoxan-4-one compounds, derivatives thereof, and methods of their synthesis and methods of their use in treating a disease or disorder in a subject in need thereof, such as diseases and disorders that are associated with telomerase activity such as cancer. The disclosed compounds may be formulated in a pharmaceutical composition for treating diseases and disorders that are associated with telomerase activity such as cancer.
3-Methylideneoxan-4-One Compounds and Substituted Derivates Thereof as Inhibitors of Telomerase
Disclosed are 3-methylideneoxan-4-one compounds, derivatives thereof, and methods of their synthesis and methods of their use in treating a disease or disorder in a subject in need thereof, such as diseases and disorders that are associated with telomerase activity such as cancer. The disclosed compounds may be formulated in a pharmaceutical composition for treating diseases and disorders that are associated with telomerase activity such as cancer.
LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND DISPLAY SUBSTRATE
A liquid crystal aligning agent includes polymer(s) from at least one of polyamic acid and group of polyimides by ring closure thereof. The acid includes a first segment structure formed by first dianhydride of formula (I) and first diamine of formula (II) or (III). X.sub.1 is an amorphous first soft segment. L is single bond, double bond, divalent or trivalent hydrocarbon group having 1 to 3 Cs. Y.sub.1 is single bond, O, NH, S, unsaturated double bond(s), or aliphatic, aromatic, heterocyclic or fused ring. One A.sub.1 and one A.sub.2, combined with Y.sub.1, are each C. Remaining A.sub.1s and A.sub.2s are each CH, CR or N. Z.sub.1 is aliphatic, aromatic, heterocyclic or fused ring. A.sub.3s and A.sub.4s are each CH, CR or N. Neither of numbers of Ns in the A.sub.1s, A.sub.2s, A.sub.3s and A.sub.4s is more than two, R.sub.1, R.sub.2 and R are each hydrogen or aliphatic hydrocarbon group.