Patent classifications
C07F9/58
PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES
The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I):
##STR00001##
as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.
PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES
The present invention provides a process for the preparation of mono- and bisacylphosphanes based on formula (I):
##STR00001##
as well as for their corresponding oxides or sulfides. The present invention further relates to photoinitiators obtainable by said process.
IMMUNOMODULATOR COMPOUNDS
Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (II):
##STR00001##
including stereoisomers and pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.3, R.sup.4, R.sup.5, R.sup.6a, R.sup.6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
MINIMALLY-INVASIVE CONTINUOUS CLINICAL MONITORING OF SMALL MOLECULES WITH ANALYTICAL ACCURACY
A dendrimer including a ring core moiety, a paramagnetic group, a linking moiety and a branching moiety for continuously probing and quantifying an analyte is provided together with methods, kits and devices for performing sensitive, accurate and durable measurements.
MINIMALLY-INVASIVE CONTINUOUS CLINICAL MONITORING OF SMALL MOLECULES WITH ANALYTICAL ACCURACY
A dendrimer including a ring core moiety, a paramagnetic group, a linking moiety and a branching moiety for continuously probing and quantifying an analyte is provided together with methods, kits and devices for performing sensitive, accurate and durable measurements.
NEW WATER SOLUBLE MONO-BRANCHED AND DI-BRANCHED COMPLEXING AGENTS, AND CORRESPONDING LANTHANIDE COMPLEXES
The invention relates to complexing agents of formula (I):
##STR00001##
wherein Chrom.sub.1, Chrom.sub.2 and Chrom.sub.3 are as defined in the description. The invention also relates to lanthanide complexes obtained from these complexing agents.
18F-labeled PSMA-targeted PET imaging agents
Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds. Representative compounds according to the application are: ##STR00001##
18F-labeled PSMA-targeted PET imaging agents
Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds. Representative compounds according to the application are: ##STR00001##
REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS
The disclosure describes chiral P(V)-based reagents and their uses for the modular, scalable, and stereospecific synthesis of chiral phosphines, phosphine oxides and particular oligonucleotides.
REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS
The disclosure describes chiral P(V)-based reagents and their uses for the modular, scalable, and stereospecific synthesis of chiral phosphines, phosphine oxides and particular oligonucleotides.