Patent classifications
C07F9/65688
Phosphonium ion channel blockers and methods for use
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: ##STR00001##
The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
ELECTROLYTES FOR TARGET ION TRANSPORT
The invention provides a zwitterionic plastic crystal (ZIPC) compound in the form of a single molecule comprising: at least one positively charged functional group carrying at least one positive charge, and at least one negatively functional group carrying at least one negative charge, wherein the positively charged functional groups and the negatively charged functional groups are covalently tethered together in the molecule, and the net charge of the zwitterionic compound is zero, and wherein the compound exhibits evidence of molecular disorder in the solid state.
Azithromycin derivatives containing a phosphonium ion as anticancer agents
This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.
Phosphonium ion channel blockers and methods for use
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: ##STR00001##
The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS
This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.
PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof:
##STR00001##
The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE
The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof:
##STR00001##
The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
HETEROATOMIC-BASED HOLE-TRANSPORT MATERIALS
Heteroatomic hole transport materials are provided. The hole transport materials include a non-carbon core: two, four, or eight aromatic groups covalently bound to the non-carbon core; a. terminal substituted diphenylamine end unit on each aromatic group: and optionally aromatic linker groups linking the aromatic groups and the substituted diphenylamine end units. In some embodiments the non-carbon core is non-carbon central atom such as Si, Ge, B.sup., P.sup.+Sn or Pb. In other embodiments, the non-carbon core is a cubic silsesquioxane. Also provided are methods for making these materials. The materials are particularly useful as hole transport materials in perovskite solar cells.
PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF
The present invention relates to new phosphaviologen derivatives, methods of making phosphaviologen derivatives, and uses thereof, including uses in electrochromic devices and organic battery materials. The phosphaviologen derivatives described herein have strong electron-accepting properties and can be used to provide phosphaviologen derivative-containing electronic materials. In certain embodiments, the phosphaviologen derivatives include dimeric phosphaviologens.
##STR00001##
Phosphaviologen derivatives, methods of making the same, and uses thereof
The present invention relates to new phosphaviologen derivatives, methods of making phosphaviologen derivatives, and uses thereof, including uses in electrochromic devices and organic battery materials. The phosphaviologen derivatives described herein have strong electron-accepting properties and can be used to provide phosphaviologen derivative-containing electronic materials. In certain embodiments, the phosphaviologen derivatives include dimeric phosphaviologens.