According to the present invention, options for materials for organic devices such as materials for organic EL elements are increased by addition of a cycloalkane, by condensation, to a polycyclic aromatic compound in which a plurality of aromatic rings are linked together by boron atoms, oxygen atoms, and the like. By using a novel cycloalkane-condensed polycyclic aromatic compound as a material for an organic EL element, for example, an organic EL element having excellent emission efficiency and element life is provided.

The present invention relates to: an anthracene derivative compound having a specific structure; and an organic light-emitting device having low-voltage driving characteristics, comprising same, and also relates to an organic light-emitting device, which employs, as a dopant compound, a polycyclic aromatic derivative compound having a specific structure together in a light-emitting layer, and thus has excellent light-emitting characteristics such as further improved low-voltage driving.

Provided herein are nucleotide prodrug compounds, their preparation and their uses, such as treating diseases or conditions of a viral infection.

The present disclosure provides an aromatic heterocyclic compound having property of thermally activated delayed fluorescence (TADF). The aromatic heterocyclic compound has a structure represented by Formula (I), in which X.sub.1 and X.sub.2 each is S, O, Se, or C; D is an electron donor, A is an electron acceptor; m is a number of the electron donor D, and the m electron donors D are the same or different; n is a number of the electron acceptor, and the n electron acceptors are the same or different; and m and n are 1 or 2. The aromatic heterocyclic compound provides a high luminescence efficiency. Organic light-emitting display devices including such aromatic heterocyclic compound have improved luminescence efficiency, lower cost and longer service life by using the aromatic heterocyclic compound as a light-emitting material, a host material, or a guest material. ##STR00001##

Provided herein are nucleotide prodrug compounds, their preparation and their uses, such as treating diseases or conditions of a viral infection.

Compounds and compositions for targeting cells expressing norepinephrine transporter, and methods of making and using the same. The compounds comprise MIBG analogs conjugated to active agents for treatment and/or diagnosis of various conditions, including neuroblastoma.

The present disclosure provides an aromatic heterocyclic compound having property of thermally activated delayed fluorescence (TADF). The aromatic heterocyclic compound has a structure represented by Formula (I), in which X.sub.1 and X.sub.2 each is S, O, Se, or C; D is an electron donor, A is an electron acceptor; m is a number of the electron donor D, and the m electron donors D are the same or different; n is a number of the electron acceptor, and the n electron acceptors are the same or different; and m and n are 1 or 2. The aromatic heterocyclic compound provides a high luminescence efficiency. Organic light-emitting display devices including such aromatic heterocyclic compound have improved luminescence efficiency, lower cost and longer service life by using the aromatic heterocyclic compound as a light-emitting material, a host material, or a guest material.

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Compounds and compositions for targeting cells expressing norepinephrine transporter, and methods of making and using the same. The compounds comprise MIBG analogs conjugated to active agents for treatment and/or diagnosis of various conditions, including neuroblastoma.

The present invention relates to disulfide masked prodrug compounds of Formula (I), nucleoside kinase bypass compositions thereof and methods that are amenable to bioactivation by a reducing agent such as glutathione: ##STR00001## Such disulfide based compounds, compositions, and methods can be useful, for example, in providing prodrugs for use as therapeutics.

Provided is a method for preparing a cyclic phosphate compound represented by formula (III) or formula (IV) and a derivative thereof. The method includes: step 1), adding a compound of formula (I), a compound of formula (II), and a solvent to a reactor, and then adding white phosphorus and a first base in sequence, followed by heating while stirring to obtain a mixed solution of reactants; and step 2), adding a second base to the mixed solution of reactants, and subjecting a resulting mixture to heating and reaction; at end of the reaction, stopping the heating and then cooling a resulting reaction product to room temperature; and adding an acid to the reactor and conducting acidification to obtain a compound of formula (III) or a compound of formula (IV).

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